Online adaptive radiation therapy aims at adapting a patient's treatment plan to their current
anatomy to account for inter-fraction variations before daily treatment delivery. As this …

Objective. Traditional radiotherapy (RT) treatment planning of non-small cell lung cancer
(NSCLC) relies on population-wide estimates of organ tolerance to minimize excess toxicity …

A typical fractionated radiotherapy (RT) course is a long and arduous process, demanding
significant financial, physical, and mental commitments from patients. Each additional …

Previous studies on personalized radiotherapy (RT) have mostly focused on baseline
patient stratification, adapting the treatment plan according to mid-treatment anatomical …

Traditionally, optimization of radiation therapy (RT) treatment plans has been done before
the initiation of RT course, using population-wide estimates for patients' response to therapy …

This monograph provides a mathematically rigorous overview of optimal fractionation in
cancer radiotherapy, which seeks to address the fundamental tradeoff of maximizing tumor …

The goal in radiotherapy for cancer is to maximize tumor-kill while limiting toxic effects on
nearby healthy anatomies. This is attempted via spatial localization of the radiation dose …

It has been recently shown that an additional therapeutic gain may be achieved if a
radiotherapy plan is altered over the treatment course using a new treatment paradigm …

The Human Genome Project (HGP) brought a revolution in medicine and has fundamentally
altered the field of biology. The concept underlying the HGP first came forth from Renato …

Radiation therapy is one of the main treatment modalities for various different cancer types.
One of the core components of personalized treatment planning is the inclusion of patient …