Malaria is still a major public health problem in Brazil, with approximately 306 000 registered
cases in 2009, but it is estimated that in the early 1940s, around six million cases of malaria …

Malaria is one of the most devastating human infectious diseases caused by Plasmodium
spp. parasites. A search for an effective and safe vaccine is the main challenge for its …

Plasmodium vivax malaria is characterized by periodic relapses of symptomatic blood stage
parasite infections likely initiated by activation of dormant liver stage parasites …

The unique relapsing nature of Plasmodium vivax infection is a major barrier to malaria
eradication. Upon infection, dormant liver-stage forms, hypnozoites, linger for weeks to …

Background Plasmodium vivax shows a small prevalence in West and Central Africa due to
the high prevalence of Duffy negative people. However, Duffy negative individuals infected …

We present evidence that a parasite with characteristics of Plasmodium vivax is being
transmitted among Duffy blood group–negative inhabitants of Kenya. Thirty-two of 4,901 …

Background A vaccine to prevent infection and disease caused by Plasmodium vivax is
needed both to reduce the morbidity caused by this parasite and as a key component in …

Plasmodium vivax is the most widespread human malaria parasite, in part because it can
form latent liver stages known as hypnozoites after transmission by female anopheline …

Malaria remains a leading cause of human morbidity and mortality due to the inability of
insecticides and chemotherapy/chemoprophylaxis to eliminate the vectors or disease …

Summary Background In August, 1997, a woman with no history of travel to malarious
regions developed Plasmodium vivax malaria. She lived in a rural area of Italy where …