Torpor and hibernation are powerful strategies enabling animals to survive periods of low
resource availability. The state of torpor results from an active and drastic reduction of an …

Alzheimer's disease (AD) is a complex age-related neurodegenerative disease, associated
with central and peripheral metabolic anomalies, such as impaired glucose utilization and …

In preclinical research on Alzheimer's disease and related tauopathies, tau phosphorylation
analysis is routinely employed in both cellular and animal models. However, recognizing the …

Tau protein, a neuronal microtubule-associated protein, becomes hyperphosphorylated in
several neurodegenerative diseases called tauopathies. Hyperphosphorylation of tau is …

In mammals, torpor/hibernation is a state that is characterized by an active reduction in
metabolic rate followed by a progressive decrease in body temperature. Torpor was …

Aging is a major risk factor for the development of neurodegenerative diseases. Alzheimer's
disease and other neurodegenerative diseases are characterized by abnormal and …

Neuroinflammation is a predisposing factor for the development of cognitive impairment and
dementia. Among the new molecules that are currently being studied, ellagic acid (EA) has …

During a long‐duration manned spaceflight mission, such as flying to Mars and beyond, all
crew members will spend a long period in an independent spacecraft with closed‐loop …

Neurodegenerative diseases (NDs) like Alzheimer's disease, multiple sclerosis, amyotrophic
lateral sclerosis, Parkinson's disease, and Huntington's disease predominantly pose a …

Introduction: Hyperphosphorylated Tau protein (PPTau) is the hallmark of tauopathic
neurodegeneration. During “synthetic torpor”(ST), a transient hypothermic state which can …