Bacteriospermia is a frequent finding in freshly extended porcine semen and can result in
detrimental effects on semen quality and longevity if left uncontrolled. The primary source of …

The adequate management of central nervous system (CNS) infections requires that
antimicrobial agents penetrate the blood–brain barrier (BBB) and achieve concentrations in …

Biofilms consist of surface-adhered bacterial communities encased in an extracellular matrix
composed of DNA, exopolysaccharides, and proteins. Extracellular DNA (eDNA) has a …

CGI 17341 (2-ethyl-5-nitro-2, 3-dihydro [2-1b] imidazo-oxazole) is a novel orally active
representative of the 5-nitroimidazole series of antimicrobial agents. At concentrations …

Antimicrobial resistance (AMR), as well as the development of biofilms in drinking water
distribution systems (DWDSs), have become an increasing concern for public health and …

The effect of degree of substitution on the antimicrobial activity of water-soluble quaternary
chitosan N-betainates was determined against Escherichia coli and Staphylococcus aureus …

Objective To determine the effects of pH on the activity of clinically relevant antibiotics
against bacterial uropathogens. Numerous factors affect antibiotic efficacy within the urinary …

Three pharmacokinetic/pharmacodynamic parameters—(i) the peak concentration to the
minimum inhibitory concentration ratio (Cmax/MIC);(ii) the area under the concentration …

The antibacterial activity of nitroxoline (NIT), an antibiotic used in the treatment of acute or
recurrent urinary tract infections caused by Escherichia coli, is decreased in the presence of …

Well characterized methylpiperazine, mono-quaternary dimethylpiperazine and di-
quaternary trimethylpiperazine derivatives of chitosan, with different degrees of substitution …