Metabolic acidosis, defined as a plasma or serum bicarbonate concentration< 22 mmol/L, is
a frequent consequence of chronic kidney disease (CKD) and occurs in~ 10–30% of …

Cerebrovascular regulation is critically dependent upon the arterial partial pressure of
carbon dioxide (P aC O 2 P_aCO_2), owing to its effect on cerebral blood flow, tissue PCO 2 …

This study explored the role of the p38 mitogen-activated protein kinase (MAPK) signaling
pathway in hippocampal neuron autophagy in rats with chronic intermittent hypoxia (CIH) …

The primary goal of the respiratory system is to match ventilation to metabolic rate, thus
maintaining blood gas homeostasis. Failure of the respiratory system to properly facilitate …

During hypercapnia (elevated partial pressure of arterial CO₂; PaCO₂) cerebral blood flow
(CBF) is elevated in order to maintain pH in the cerebral tissues; mean arterial pressure …

Metabolic acidosis, defined as a plasma or serum bicarbonate concentration< 22mmol/L, is
a frequent consequence of chronic kidney disease (CKD) and occurs in~ 10–30% of …