Resistance of lenvatinib in hepatocellular carcinoma

J Guo, J Zhao, Q Xu, D Huang - Current Cancer Drug Targets, 2022 - ingentaconnect.com
Lenvatinib is a multikinase inhibitor which mainly hinders liver cancer proliferation by
inhibiting angiogenesis. In 2018, Lenvatinib was approved for the first-line treatment of …

The application of nanoparticles in immunotherapy for hepatocellular carcinoma

X Hu, H Zhu, X He, J Chen, L Xiong, Y Shen, J Li… - Journal of Controlled …, 2023 - Elsevier
Hepatocellular carcinoma (HCC) remains one of the leading causes of cancer-related
deaths worldwide, however, current clinical diagnostic and treatment approaches remain …

[HTML][HTML] Long noncoding RNA LINC01234 promotes hepatocellular carcinoma progression through orchestrating aspartate metabolic reprogramming

M Chen, C Zhang, W Liu, X Du, X Liu, B Xing - Molecular Therapy, 2022 - cell.com
Amino acids metabolism, especially aspartate metabolism, is often altered in human cancers
including hepatocellular carcinoma (HCC) and this metabolic remodeling is required for …

[HTML][HTML] TUBA1C is a prognostic marker in low-grade glioma and correlates with immune cell infiltration in the tumor microenvironment

H Zhu, X Hu, L Gu, Z Jian, L Li, S Hu, S Qiu… - Frontiers in …, 2021 - frontiersin.org
TUBA1C, a microtubule component, contributes to the development of several cancers. Our
purpose was to study the expression of TUBA1C, its potential prognostic value, and its …

Repolarization of macrophages to improve sorafenib sensitivity for combination cancer therapy

L Huang, R Xu, W Li, L Lv, C Lin, X Yang, Y Yao… - Acta Biomaterialia, 2023 - Elsevier
Sorafenib is the first line drug for hepatocellular carcinoma (HCC) therapy. However, HCC
patients usually acquire resistance to sorafenib treatment within 6 months. Recent …

[HTML][HTML] Tubulin alpha 1b is associated with the immune cell infiltration and the response of HCC patients to immunotherapy

X Hu, H Zhu, B Chen, X He, Y Shen, X Zhang, W Chen… - Diagnostics, 2022 - mdpi.com
Tubulin alpha 1b (TUBA1B) is an important microtubule isoform that is involved in the
formation of the cytoskeleton. The objective of our study was to explore the potential of …

[HTML][HTML] Oncogenic lncRNA BBOX1-AS1 promotes PHF8-mediated autophagy and elicits sorafenib resistance in hepatocellular carcinoma

H Tao, Y Zhang, J Li, J Liu, T Yuan, W Wang… - Molecular Therapy …, 2023 - cell.com
Some long non-coding RNAs (lncRNAs) have been documented to be involved in cancer
progression and anticancer drug resistance in hepatocellular carcinoma (HCC). Thus …

[HTML][HTML] The interplay between noncoding RNAs and drug resistance in hepatocellular carcinoma: the big impact of little things

Y Fang, XL Zhang, HF Huang, Z Zeng - Journal of Translational Medicine, 2023 - Springer
Hepatocellular carcinoma (HCC) is the leading cause of cancer-related death in people, and
a common primary liver cancer. Lacking early diagnosis and a high recurrence rate after …

[HTML][HTML] Pyroptosis-related LncRNA signature predicts prognosis and is associated with immune infiltration in hepatocellular carcinoma

ZK Liu, KF Wu, RY Zhang, LM Kong, RZ Shang… - Frontiers in …, 2022 - frontiersin.org
Pyroptosis is an inflammatory form of programmed cell death that is involved in various
cancers, including hepatocellular carcinoma (HCC). Long non-coding RNAs (lncRNAs) …

[HTML][HTML] Long Non-Coding RNA LINC01572 Promotes Hepatocellular Carcinoma Progression via Sponging miR-195-5p to Enhance PFKFB4-Mediated Glycolysis …

S Lai, Z Quan, Y Hao, J Liu, Z Wang, L Dai… - Frontiers in Cell and …, 2021 - frontiersin.org
Background: Accumulating evidence indicates that type 2 diabetes mellitus (T2DM) is a risk
factor for hepatocellular carcinoma (HCC), and T2DM-associated HCC represents a …