[HTML][HTML] SARS-CoV-2 Omicron variant: recent progress and future perspectives

Y Fan, X Li, L Zhang, S Wan, L Zhang… - Signal transduction and …, 2022 - nature.com
Since the outbreak of the coronavirus disease 2019 (COVID-19) pandemic, there have been
a few variants of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), one of …

A detailed overview of SARS-CoV-2 omicron: its sub-variants, mutations and pathophysiology, clinical characteristics, immunological landscape, immune escape, and …

S Chatterjee, M Bhattacharya, S Nag, K Dhama… - Viruses, 2023 - mdpi.com
The COVID-19 pandemic has created significant concern for everyone. Recent data from
many worldwide reports suggest that most infections are caused by the Omicron variant and …

COVID-19 vaccine update: vaccine effectiveness, SARS-CoV-2 variants, boosters, adverse effects, and immune correlates of protection

WY Chi, YD Li, HC Huang, TEH Chan, SY Chow… - Journal of biomedical …, 2022 - Springer
Abstract Coronavirus Disease 2019 (COVID-19) has been the most severe public health
challenge in this century. Two years after its emergence, the rapid development and …

Real-world effectiveness of early molnupiravir or nirmatrelvir–ritonavir in hospitalised patients with COVID-19 without supplemental oxygen requirement on admission …

CKH Wong, ICH Au, KTK Lau, EHY Lau… - The Lancet Infectious …, 2022 - thelancet.com
Background Data on the effectiveness of oral antivirals in patients with mild-to-moderate
COVID-19 are urgently needed. This retrospective cohort study aimed to evaluate the …

Omicron: what makes the latest SARS-CoV-2 variant of concern so concerning?

C Jung, D Kmiec, L Koepke, F Zech, T Jacob… - Journal of …, 2022 - Am Soc Microbiol
Emerging strains of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the
causative agent of the coronavirus disease 2019 (COVID-19) pandemic, that show …

SARS-CoV-2 Omicron is an immune escape variant with an altered cell entry pathway

BJ Willett, J Grove, OA MacLean, C Wilkie… - Nature …, 2022 - nature.com
Vaccines based on the spike protein of SARS-CoV-2 are a cornerstone of the public health
response to COVID-19. The emergence of hypermutated, increasingly transmissible variants …

SARS-CoV-2 requires acidic pH to infect cells

AJB Kreutzberger, A Sanyal… - Proceedings of the …, 2022 - National Acad Sciences
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) cell entry starts with
membrane attachment and ends with spike (S) protein–catalyzed membrane fusion …

SARS-CoV-2 and innate immunity: the good, the bad, and the “goldilocks”

BL Sievers, MTK Cheng, K Csiba, B Meng… - Cellular & Molecular …, 2024 - nature.com
An ancient conflict between hosts and pathogens has driven the innate and adaptive arms of
immunity. Knowledge about this interplay can not only help us identify biological …

Coronavirus disease 2019 (COVID‐19)–related smell and taste impairment with widespread diffusion of severe acute respiratory syndrome–coronavirus‐2 (SARS …

P Boscolo‐Rizzo, G Tirelli, P Meloni… - International forum of …, 2022 - Wiley Online Library
Background The aim of this study was to estimate the prevalence of self‐reported
chemosensory dysfunction in a study cohort of subjects who developed a mild‐to‐moderate …

Replication kinetics and infectivity of SARS-CoV-2 variants of concern in common cell culture models

L Mautner, M Hoyos, A Dangel, C Berger, A Ehrhardt… - Virology journal, 2022 - Springer
Abstract Background During the ongoing Covid-19 pandemic caused by the emerging virus
SARS-CoV-2, research in the field of coronaviruses has expanded tremendously. The …