Despite advances in neurosurgery, chemotherapy and radiotherapy, glioblastoma remains
one of the most treatment-resistant CNS malignancies, and the tumour inevitably recurs. The …

Background Glioblastoma (GBM) is the most common and aggressive malignant brain tumor
in adults. Current treatment options at diagnosis are multimodal and include surgical …

To follow the revision of the fourth edition of WHO classification and the recent progress on
the management of diffuse gliomas, the joint guideline committee of Chinese Glioma …

Importance Per the World Health Organization 2016 integrative classification, newly
diagnosed glioblastomas are separated into isocitrate dehydrogenase gene 1 or 2 (IDH) …

Importance Glioblastoma multiforme (GBM) remains almost invariably fatal despite optimal
surgical and medical therapy. The association between the extent of tumor resection (EOR) …

Abstract The US Food and Drug Administration (FDA) approved 5-aminolevulinic acid (5-
ALA; Gleolan®; photonamic GmbH and Co. KG) for use as an intraoperative optical imaging …

Gliomas are one of the most common types of primary brain tumors and have remained
particularly challenging to treat. This review illustrates a multidisciplinary approach to the …

Radiographic endpoints including response and progression are important for the
evaluation of new glioblastoma therapies. The current RANO criteria was developed to …

Over the past two decades, synergistic innovations in imaging technology have resulted in a
revolution in which a range of biomedical applications are now benefiting from fluorescence …

Surgical resection plays a central role in the management of gliomas. In this study, we
review the evidence in support of extent of resection to improve survival, symptom …