Open-chain tetrapyrroles are ubiquitous and abundant in living organisms (algae, animals,
bacteria, and plants), including examples such as bilirubin, biliverdin, phycocyanobilin …

A strategy for the synthesis of bacteriochlorophyll a relies on joining AD and BC halves that
contain the requisite stereochemical configurations of the target macrocycle. The BC half (1) …

The photosynthetic tetrapyrroles and their catabolic products (phyllobilins) share similar
structural features in the southern rim encompassing rings C–E with variation in the degree …

Chlorophylls provide the basis for photosynthesis and thereby most life on Earth. Besides
their involvement in primary charge separation in the reaction center, they serve as light …

Photodynamic therapy (PDT) is a non-invasive and tumour-specific therapy.
Photosensitizers (PSs)(essential ingredients in PDT) aggregate easily owing to their …

In view of the existing controversy around the origin of the photosynthesis and, therefore, the
first photosynthetic pigments, our work focuses on the theoretical study of a hypothetical first …

Synthetic bacteriochlorins, analogues of native bacteriochlorophylls, provide absorption in
the near-infrared spectral region and hence are valuable for fundamental studies in …

The development of chromophores that absorb in the near-infrared (NIR) region beyond
1000 nm underpins numerous applications in medical and energy sciences, yet also …

Phyllobilins, derived from the breakdown of chlorophyll in plants, are acyclic tetrapyrroles
that bear the signature ring E of the parent macrocycle. Few synthetic studies have …

A planned total synthesis of photosynthetic tetrapyrrole macrocycles installs essential
stereochemical features in early precursors via established asymmetric methodology. Key …