The role of innate immunity in natural elite controllers of HIV-1 infection

Y Shi, J Su, R Chen, W Wei, Z Yuan, X Chen… - Frontiers in …, 2022 - frontiersin.org
The natural process of human immunodeficiency virus type 1 (HIV-1) infection is
characterized by high viral load, immune cell exhaustion, and immunodeficiency, which …

Astrocytes are HIV reservoirs in the brain: a cell type with poor HIV infectivity and replication but efficient cell‐to‐cell viral transfer

S Valdebenito, P Castellano, D Ajasin… - Journal of …, 2021 - Wiley Online Library
The major barrier to eradicating Human immunodeficiency virus‐1 (HIV) infection is the
generation of tissue‐associated quiescent long‐lasting viral reservoirs refractory to therapy …

How elite controllers and posttreatment controllers inform our search for an HIV-1 cure

JZ Li, JN Blankson - The Journal of clinical investigation, 2021 - Am Soc Clin Investig
A small percentage of people living with HIV-1 can control viral replication without
antiretroviral therapy (ART). These patients are called elite controllers (ECs) if they are able …

RPLP1 restricts HIV-1 transcription by disrupting C/EBPβ binding to the LTR

W Yang, H Wang, Z Li, L Zhang, J Liu… - Nature …, 2024 - nature.com
Long-term non-progressors (LTNPs) of HIV-1 infection may provide important insights into
mechanisms involved in viral control and pathogenesis. Here, our results suggest that the …

MiR-155 Negatively Regulates Anti-Viral Innate Responses among HIV-Infected Progressors

P Pawar, J Gokavi, S Wakhare, R Bagul, U Ghule… - Viruses, 2023 - mdpi.com
HIV infection impairs host immunity, leading to progressive disease. An anti-retroviral
treatment efficiently controls viremia but cannot completely restore the immune dysfunction …

Koalas vaccinated against Koala retrovirus respond by producing increased levels of interferon-gamma

O Olagoke, BL Quigley, P Timms - Virology Journal, 2020 - Springer
Koala retrovirus (KoRV) is believed to be in an active state of endogenization into the koala
genome. KoRV is present as both an endogenous and exogenous infection in all koalas in …

Efetividade do pré-natal especializado para o controle da Infecção pelo HIV na gestação, no puerpério e na transmissão vertical, em um serviço de referência de …

SAP São Pedro - 2022 - repositorio.ufba.br
Introdução–A transmissão de infecção pelo HIV de mãe para filho, durante a gestação, o
trabalho de parto, o nascimento e o aleitamento, ainda constitui um grave problema de …