Since its discovery six decades ago, the predatory bacterium Bdellovibrio bacteriovorus has
sparked recent interest as a potential remedy to the antibiotic resistance crisis. Here we give …

Predatory bacteria have been increasingly known for their ubiquity in environments and
great functional potentials in controlling unwanted microorganisms. Fundamental …

Microbes including bacteria are required to respond to their often continuously changing
ecological niches in order to survive. While many signaling molecules are produced as …

Diversifying radiation of domain families within specific lineages of life indicates the
importance of their functionality for the organisms. The foundation for the diversifying …

The PilZ domain‐containing protein, PlzA, is the only known cyclic di‐GMP binding protein
encoded by all Lyme disease spirochetes. PlzA has been implicated in the regulation of …

Solute carrier proteins (SLCs) are pivotal for maintaining cellular homeostasis by
transporting small molecules across cellular membranes. Recent discoveries have …

The bacterial predator Bdellovibrio bacteriovorus is a model for the wider phenomenon of
bacteria: bacteria predation, and the specialization required to achieve a lifestyle dependent …

The bacterial predator Bdellovibrio bacteriovorus is considered to be obligatorily prey (host)-
dependent (HD), and thus unable to form biofilms. However, spontaneous host-independent …

Highlights•Bacteria utilize nucleotide second messengers such as (p) ppGpp as stress
regulators.•Crosstalk exists between nucleotide second messenger signaling pathways.•(p) …

Bacteria possess well-orchestrated signal transduction mechanisms, such as nucleotide
second messengers, to tune gene regulation for adaption and survival in variety of …