Into rather unexplored terrain—Transcellular transport across the blood–brain barrier

M De Bock, V Van Haver, RE Vandenbroucke… - Glia, 2016 - Wiley Online Library
Efficient neuronal signaling in the central nervous system strictly depends on a well‐
balanced microenvironment around glial cells, synapses, and axons. Unique features of the …

Techniques for evaluating the ATP-gated ion channel P2X7 receptor function in macrophages and microglial cells

R Leite-Aguiar, VG Bello-Santos, NG Castro… - Journal of …, 2024 - Elsevier
Resident macrophages are tissue-specific innate immune cells acting as sentinels,
constantly patrolling their assigned tissue to maintain homeostasis, and quickly responding …

Mapping the electrostatic profiles of cellular membranes

S Eisenberg, E Haimov, GFW Walpole… - Molecular Biology of …, 2021 - Am Soc Cell Biol
Anionic phospholipids can confer a net negative charge on biological membranes. This
surface charge generates an electric field that serves to recruit extrinsic cationic proteins …

TRPing on the pore phenomenon: what do we know about transient receptor potential ion channel-related pore dilation up to now?

LGB Ferreira, RX Faria - Journal of bioenergetics and biomembranes, 2016 - Springer
Ion channels allow for rapid ion diffusion through the plasma membrane. In some conditions,
ion channels induce changes in the critical plasma membrane permeability that permit 900 …

8-Hydroxy-2-(1H-1, 2, 3-triazol-1-yl)-1, 4-naphtoquinone derivatives inhibited P2X7 Receptor-Induced dye uptake into murine Macrophages

PAF Pacheco, RMS Galvão, AFM Faria… - Bioorganic & Medicinal …, 2019 - Elsevier
Abstract Extracellular adenosine 5′-triphosphate (ATP) triggers the P2X7 receptor (P2X7R)
ionic channel to stimulate the release of the interleukin-IL-1β cytokine into macrophages …

P2X7R large pore is partially blocked by pore forming proteins antagonists in astrocytes

RX Faria, RAM Reis, LGB Ferreira… - Journal of bioenergetics …, 2016 - Springer
Abstract The ATP-gated P2X7R (P2X7R) is a channel, which is involved in events, such as
inflammation, cell death, and pain. The most intriguing event concerning P2X7R functions is …

[PDF][PDF] Shifting Gears Towards the Red: Novel Boron-Based Fluorophores for Bioimaging Applications

A Marfavi - 2023 - core.ac.uk
Near-infrared (NIR) fluorescence imaging is an emerging modality that has experienced
recent technological advancements, for use in both clinical practice and biomedical …

[HTML][HTML] Patch Clamping in Combination with Fluorescence Is a Reliable Technique for Studying Pore-Forming Ion Channels

GP Teixeira, L Rocha, RX Faria - Patch Clamp Technique-Current …, 2024 - intechopen.com
Ion channels play essential roles in the functional balance of cells, whether in the context of
electrical balance or in the activation of signaling pathways for specific processes. Pore …

P2X receptors

A Nicke, T Grutter, TM Egan - The Oxford handbook of neuronal …, 2018 - books.google.com
There may be no molecule more versatile than adenosine triphosphate (ATP). In large part,
this is because ATP provides a high-energy phosphate bond that is the primary currency of …

Papel do receptor de potencial transitório vanilóide subtipo 1 sobre células do sistema imunoendócrino envolvidas na produção de glicocorticoides

LGB Ferreira - 2018 - arca.fiocruz.br
O eixo hipotálamo-hipófise-adrenal (HPA) é um complexo circuito de interação entre os
componentes do sistema neuroimunoendócrino. Em vista da forte influência de vários …