Interplay between the gut-brain axis, obesity and cognitive function

A Agustí, MP García-Pardo, I López-Almela… - Frontiers in …, 2018 - frontiersin.org
Obesity continues to be one of the major public health problems due to its high prevalence
and co-morbidities. Common co-morbidities not only include cardiometabolic disorders but …

The association of depression and all-cause and cause-specific mortality: an umbrella review of systematic reviews and meta-analyses

MO Machado, N Veronese, M Sanches, B Stubbs… - BMC medicine, 2018 - Springer
Background Depression is a prevalent and disabling mental disorder that frequently co-
occurs with a wide range of chronic conditions. Evidence has suggested that depression …

Mapping risk factors for depression across the lifespan: an umbrella review of evidence from meta-analyses and Mendelian randomization studies

CA Köhler, E Evangelou, B Stubbs, M Solmi… - Journal of psychiatric …, 2018 - Elsevier
The development of depression may involve a complex interplay of environmental and
genetic risk factors. PubMed and PsycInfo databases were searched from inception through …

Effects of different doses of esketamine intervention on postpartum depressive symptoms in cesarean section women: a randomized, double-blind, controlled clinical …

SQ Yang, YY Zhou, ST Yang, XY Mao, L Chen… - Journal of Affective …, 2023 - Elsevier
Background The optimal dosage and method of esketamine for postpartum depressive
symptoms (PDS) are unclear. We conducted a randomized controlled trial (RCT) to …

Host-Pathogen Molecular Factors Contribute to the Pathogenesis of Rhizopus spp. in Diabetes Mellitus

B Morales-Franco, M Nava-Villalba… - … tropical medicine reports, 2021 - Springer
Abstract Purpose of Review Infectious diseases represent up to 12% of all deaths in people
with diabetes mellitus (DM). The development and progression of DM generate a chronic …

Phenomenology, epidemiology and aetiology of postpartum psychosis: a review

A Perry, K Gordon-Smith, L Jones, I Jones - Brain sciences, 2021 - mdpi.com
Postpartum psychoses are a severe form of postnatal mood disorders, affecting 1–2 in every
1000 deliveries. These episodes typically present as acute mania or depression with …

Gut dysbiosis dysregulates central and systemic homeostasis via suboptimal mitochondrial function: assessment, treatment and classification implications

G Anderson, M Maes - Current Topics in Medicinal Chemistry, 2020 - ingentaconnect.com
The gut and mitochondria have emerged as two important hubs at the cutting edge of
research across a diverse array of medical conditions, including most psychiatric conditions …

Glymphatic dysfunction induced oxidative stress and neuro-inflammation in major depression disorders

S Gu, Y Li, Y Jiang, JH Huang, F Wang - Antioxidants, 2022 - mdpi.com
Major Depression disorder (MDD) is a potentially life-threatening mental illness, however,
many patients have a poor response to current treatments. Recent studies have suggested …

Shared pathways for neuroprogression and somatoprogression in neuropsychiatric disorders

G Morris, BK Puri, AJ Walker, M Maes… - Neuroscience & …, 2019 - Elsevier
Activated immune-inflammatory, oxidative and nitrosative stress (IO&NS) pathways and
consequent mitochondrial aberrations are involved in the pathophysiology of psychiatric …

Neurodevelopmental pathways in bipolar disorder

S Kloiber, JD Rosenblat, MI Husain, A Ortiz… - Neuroscience & …, 2020 - Elsevier
Aberrations in neurodevelopmental trajectories have been implicated in the neurobiology of
several mental disorders and evidence indicates a pathophysiological and genetic overlap …