Due to its pivotal role in autonomic networks and interoception, the vagus attracts continued
interest from both basic scientists and therapists of various clinical disciplines. In particular …

The cephalic phase insulin response (CPIR) is classically defined as a head receptor-
induced early release of insulin during eating that precedes a postabsorptive rise in blood …

Taste buds are innervated by neurons whose cell bodies reside in cranial sensory ganglia.
Studies on the functional properties and connectivity of these neurons are hindered by the …

Mammalian taste buds are comprised of specialized neuroepithelial cells that act as sensors
for molecules that provide nutrition (eg, carbohydrates, amino acids, and salts) and those …

Are the symptoms of autism caused by a treatable metabolic syndrome that traces to the
abnormal persistence of a normal, alternative functional state of mitochondria? A small …

A key process in central sensory circuit development involves activity-dependent pruning of
exuberant terminals. Here, we studied gustatory terminal field maturation in the postnatal …

Strong evidence supports a major role for heterodimers of the type 1 taste receptor (T1R)
family in the taste transduction of sugars (T1R2+ T1R3) and amino acids (T1R1+ T1R3), but …

The nucleus of the solitary tract is a potential site for taste–visceral interactions. Connections
from the caudal, visceral area of the nucleus (cNST) to the rostral, gustatory zone (rNST) …

Taste buds contain multiple cell types with each type expressing receptors and transduction
components for a subset of taste qualities. The sour sensing cells, Type III cells, release …

Recent findings from our laboratory demonstrated that the rostral nucleus of the solitary tract
(rNST) retains some responsiveness to sugars in double-knock-out mice lacking either the …