Does vitamin C influence neurodegenerative diseases and psychiatric disorders?

J Kocot, D Luchowska-Kocot, M Kiełczykowska, I Musik… - Nutrients, 2017 - mdpi.com
Vitamin C (Vit C) is considered to be a vital antioxidant molecule in the brain. Intracellular Vit
C helps maintain integrity and function of several processes in the central nervous system …

Energy metabolism of the brain, including the cooperation between astrocytes and neurons, especially in the context of glycogen metabolism

A Falkowska, I Gutowska, M Goschorska… - International journal of …, 2015 - mdpi.com
Glycogen metabolism has important implications for the functioning of the brain, especially
the cooperation between astrocytes and neurons. According to various research data, in a …

[图书][B] Handbook of vitamins

J Zempleni, JW Suttie, JF Gregory III, PJ Stover - 2013 - books.google.com
Within the last few years, knowledge about vitamins has increased dramatically. This new
edition of a bestseller presents comprehensive summaries that analyze the chemical …

GLUT3 induced by AMPK/CREB1 axis is key for withstanding energy stress and augments the efficacy of current colorectal cancer therapies

W Dai, Y Xu, S Mo, Q Li, J Yu, R Wang, Y Ma… - Signal transduction and …, 2020 - nature.com
Cancer cells are usually characterized by hyperactive glucose metabolism, which can often
lead to glucose scarcity; thus, alternative pathways to rewire cancer metabolism are …

Old things new view: ascorbic acid protects the brain in neurodegenerative disorders

A Covarrubias-Pinto, AI Acuña, FA Beltrán… - International journal of …, 2015 - mdpi.com
Ascorbic acid is a key antioxidant of the Central Nervous System (CNS). Under brain activity,
ascorbic acid is released from glial reservoirs to the synaptic cleft, where it is taken up by …

Redox mechanisms in neurodegeneration: from disease outcomes to therapeutic opportunities

JI Sbodio, SH Snyder, BD Paul - Antioxidants & Redox Signaling, 2019 - liebertpub.com
Significance: Once considered to be mere by-products of metabolism, reactive oxygen,
nitrogen and sulfur species are now recognized to play important roles in diverse cellular …

A failure in energy metabolism and antioxidant uptake precede symptoms of Huntington's disease in mice

AI Acuña, M Esparza, C Kramm, FA Beltrán… - Nature …, 2013 - nature.com
Huntington's disease has been associated with a failure in energy metabolism and oxidative
damage. Ascorbic acid is a powerful antioxidant highly concentrated in the brain where it …

[HTML][HTML] Gestational exposure to air pollutants perturbs metabolic and placenta-fetal phenotype

A Ganguly, S Ghosh, BC Shin, M Touma… - Reproductive …, 2024 - Elsevier
Air pollution (AP) is detrimental to pregnancies including increasing risk factors of
gestational diabetes mellitus. We hypothesized that exposure to AP causes cardiovascular …

Visualizing sweetness: increasingly diverse applications for fluorescent-tagged glucose bioprobes and their recent structural modifications

WH Kim, J Lee, DW Jung, DR Williams - Sensors, 2012 - mdpi.com
Glucose homeostasis is a fundamental aspect of life and its dysregulation is associated with
important diseases, such as cancer and diabetes. Traditionally, glucose radioisotopes have …

Neuron‐glia (mis) interactions in brain energy metabolism during aging

G Mayorga‐Weber, FJ Rivera… - Journal of Neuroscience …, 2022 - Wiley Online Library
Life expectancy in humans is increasing, resulting in a growing aging population, that is
accompanied by an increased disposition to develop cognitive deterioration …