The development of new drugs will certainly benefit from an ever improving knowledge of
the living beings chemistry. However, identification of drugable molecules within the …

The short history, specific features and future prospects of research of microbial metabolites,
including antibiotics and other bioactive metabolites, are summarized. The microbial origin …

Actinomycetes are virtually unlimited sources of novel compounds with many therapeutic
applications and hold a prominent position due to their diversity and proven ability to …

During 1914 to 1939, Selman A. Waksman had been consistently systematically screening
soil bacteria and fungi to find an antibiotic for tuberculosis. In 1939, he discovers the effect of …

Covering: 1993–2014 (July) To alleviate the dereplication holdup, which is a major
bottleneck in natural products discovery, scientists have been conducting their research …

For years, fungi have served as repositories of bioactive secondary metabolites that form the
backbone of many existing drugs. With the global rise in infections associated with …

For thousands of years medicine and natural products have been closely linked through the
use of traditional medicines and natural poisons. Mushrooms have an established history of …

Endophytes, which are widely found in host plants and have no harmful effects, are a vital
biological resource. Plant endophytes promote plant growth and enhance plants' resistance …

New antimicrobial agents are desperately needed to combat the increasing number of
antibiotic resistant strains of pathogenic microorganisms. Natural products remain the most …

Chemotherapy is one of the main treatments used to combat cancer. A great number of
antitumor compounds are natural products or their derivatives, mainly produced by …