The use of bacterial cells as agents of medical therapy has a long history. Research that was
ignited over a century ago with the accidental infection of cancer patients has matured into a …

Recent advances in synthetic biology and biological system engineering have allowed the
design and construction of engineered live biotherapeutics targeting a range of human …

Bacteria can sense their environment, distinguish between cell types, and deliver proteins to
eukaryotic cells. Here, we engineer the interaction between bacteria and cancer cells to …

Protein-based micelles have shown significant potential for tumor-targeted delivery of anti-
cancer drugs. In this light, self-assembled nanocarriers based on GRAS (Generally …

Breast cancer is the most global dominant cancer among females. Although there are
continuously growing strategies to develop new therapies, the outcomes are usually …

The ability of bacteria to mediate gene transfer has only recently been established and these
observations have led to the utilization of various bacterial strains in gene therapy. The types …

Most bacteria pathogenic for humans have closely related nonpathogenic counterparts that
live as saprophytes, commensals or even symbionts (mutualists) in similar or different …

Some anaerobic and facultative anaerobic bacteria have been used experimentally as
anticancer agents because of their selective growth in the hypoxia regions of solid tumors …

Evolutionary observations have often served as an inspiration for biological design.
Decoding of the central dogma of life at a molecular level and understanding of the cellular …

Current conventional treatments for cancer lack tumour selectivity resulting in the destruction
of healthy tissue and severe adverse effects to the patient in addition to limiting the …