Cellular and molecular regulation of the programmed death-1/programmed death ligand system and its role in multiple sclerosis and other autoimmune diseases
J Ibañez-Vega, C Vilchez, K Jimenez, C Guevara… - Journal of …, 2021 - Elsevier
Abstract Programmed Cell Death 1 (PD-1) receptor and its ligands (PD-Ls) are essential to
maintain peripheral immune tolerance and to avoid tissue damage. Consequently, altered …
maintain peripheral immune tolerance and to avoid tissue damage. Consequently, altered …
Immunological synapse predicts effectiveness of chimeric antigen receptor cells
Chimeric antigen receptor (CAR)-modified T cell therapy has the potential to improve the
overall survival of patients with malignancies by enhancing the effectiveness of CAR T cells …
overall survival of patients with malignancies by enhancing the effectiveness of CAR T cells …
Evaluation of single-cell cytokine secretion and cell-cell interactions with a hierarchical loading microwell chip
Comprehensive evaluation of single T cell functions such as cytokine secretion and cytolysis
of target cells is greatly needed in adoptive cell therapy (ACT) but has never been fully …
of target cells is greatly needed in adoptive cell therapy (ACT) but has never been fully …
[HTML][HTML] Activation of NK cells and disruption of PD-L1/PD-1 axis: two different ways for lenalidomide to block myeloma progression
Natural Killer (NK) cells play a critical role against tumor cells in hematological
malignancies. Their activating receptors are essential in tumor cell killing. In Multiple …
malignancies. Their activating receptors are essential in tumor cell killing. In Multiple …
Role of actin cytoskeleton reorganization in polarized secretory traffic at the immunological synapse
V Calvo, M Izquierdo - Frontiers in cell and developmental biology, 2021 - frontiersin.org
T cell receptor (TCR) and B cell receptor (BCR) stimulation by antigen presented on an
antigen-presenting cell (APC) induces the formation of the immune synapse (IS), the …
antigen-presenting cell (APC) induces the formation of the immune synapse (IS), the …
The role of immunological synapse in predicting the efficacy of chimeric antigen receptor (CAR) immunotherapy
Abstract Chimeric Antigen Receptor (CAR) immunotherapy utilizes genetically-engineered
immune cells that express a unique cell surface receptor that combines tumor antigen …
immune cells that express a unique cell surface receptor that combines tumor antigen …
Regulation of natural killer cell function by STAT3
NA Cacalano - Frontiers in immunology, 2016 - frontiersin.org
Natural killer (NK) cells, key members of a distinct hematopoietic lineage, innate lymphoid
cells, are not only critical effectors that mediate cytotoxicity toward tumor and virally infected …
cells, are not only critical effectors that mediate cytotoxicity toward tumor and virally infected …
Signaling pathway and dysregulation of PD1 and its ligands in lymphoid malignancies
Y Xia, LJ Medeiros, KH Young - … et Biophysica Acta (BBA)-Reviews on …, 2016 - Elsevier
Tumor cells evade immune destruction, at least partially, by upregulating inhibitory signals to
limit effector T cell activation. Programmed death 1 (PD-1) is one of the most critical co …
limit effector T cell activation. Programmed death 1 (PD-1) is one of the most critical co …
Photoactivatable materials for versatile single-cell patterning based on the photocaging of cell-anchoring moieties through lipid self-assembly
S Yamahira, R Misawa, T Kosaka, M Tan… - Journal of the …, 2022 - ACS Publications
Versatile methods for patterning multiple types of cells with single-cell resolution have
become an increasingly important technology for cell analysis, cell-based device …
become an increasingly important technology for cell analysis, cell-based device …