Selenium is an essential microelement required for a number of biological functions.
Selenium—and more specifically the amino acid selenocysteine—is present in at least 25 …

Initially adopted as a mucolytic about 60 years ago, the cysteine prodrug N-acetylcysteine
(NAC) is the standard of care to treat paracetamol intoxication, and is included on the World …

Although most patients recover from acute COVID-19, some experience postacute sequelae
of severe acute respiratory syndrome coronavirus 2 infection (PASC). One subgroup of …

Hydropersulfides (RSSH) are believed to serve important roles in vivo, including as
scavengers of damaging oxidants and electrophiles. The α-effect makes RSSH not only …

Hydrogen sulfide (H 2 S) was once considered to have only toxic properties, until it was
discovered to be an endogenous signaling molecule. The effects of H 2 S are dose …

To enable survival in adverse conditions, cancer cells undergo global metabolic
adaptations. The amino acid cysteine actively contributes to cancer metabolic remodelling …

Oxidation–reduction (redox) reactions are central to the existence of life. Reactive species of
oxygen, nitrogen and sulfur mediate redox control of a wide range of essential cellular …

Gut microbiota act beyond the gastrointestinal tract to regulate the physiology of the host.
However, their contribution to the antioxidant capacity of the host remains largely …

Cellular redox homeostasis is an essential and dynamic process that ensures the balance
between reducing and oxidizing reactions within cells and regulates a plethora of biological …

Significance: Persulfides/polysulfides are sulfur-catenated molecular species (ie, R-Sn-R′,
n> 2; R-Sn-H, n> 1, with R= cysteine, glutathione, and proteins), such as cysteine persulfide …