Losing the dogmatic view of cerebral autoregulation

P Brassard, L Labrecque, JD Smirl… - Physiological …, 2021 - Wiley Online Library
Abstract In 1959, Niels Lassen illustrated the cerebral autoregulation curve in the classic
review article entitled Cerebral Blood Flow and Oxygen Consumption in Man. This concept …

Neurocognitive function after cardiac surgery: from phenotypes to mechanisms

M Berger, N Terrando, SK Smith… - …, 2018 - pmc.ncbi.nlm.nih.gov
For half a century, we have known that some patients experience neurocognitive dysfunction
after cardiac surgery, yet defining its incidence, course, and causes remains challenging …

A review of postoperative cognitive dysfunction and neuroinflammation associated with cardiac surgery and anaesthesia

AE Van Harten, TWL Scheeren, AR Absalom - Anaesthesia, 2012 - Wiley Online Library
Postoperative cognitive dysfunction is receiving increasing attention, particularly as it mainly
affects the (growing) elderly population. Until recently, cognitive deficits after cardiac surgery …

Predicting the limits of cerebral autoregulation during cardiopulmonary bypass

B Joshi, M Ono, C Brown, K Brady… - Anesthesia & …, 2012 - journals.lww.com
BACKGROUND: Mean arterial blood pressure (MAP) targets are empirically chosen during
cardiopulmonary bypass (CPB). We have previously shown that near-infrared spectroscopy …

Arterial pressure above the upper cerebral autoregulation limit during cardiopulmonary bypass is associated with postoperative delirium

D Hori, C Brown, M Ono, T Rappold… - British journal of …, 2014 - academic.oup.com
Background Mean arterial pressure (MAP) below the lower limit of cerebral autoregulation
during cardiopulmonary bypass (CPB) is associated with complications after cardiac …

[HTML][HTML] Duration and magnitude of blood pressure below cerebral autoregulation threshold during cardiopulmonary bypass is associated with major morbidity and …

M Ono, K Brady, RB Easley, C Brown, M Kraut… - The Journal of thoracic …, 2014 - Elsevier
Objectives Optimizing blood pressure using near-infrared spectroscopy monitoring has been
suggested to ensure organ perfusion during cardiac surgery. Near-infrared spectroscopy is …

Blood pressure excursions below the cerebral autoregulation threshold during cardiac surgery are associated with acute kidney injury

M Ono, GJ Arnaoutakis, DM Fine, K Brady… - Critical care …, 2013 - journals.lww.com
Objectives: To determine whether mean arterial blood pressure excursions below the lower
limit of cerebral blood flow autoregulation during cardiopulmonary bypass are associated …

Risks for impaired cerebral autoregulation during cardiopulmonary bypass and postoperative stroke

M Ono, B Joshi, K Brady, RB Easley… - British journal of …, 2012 - academic.oup.com
Background Impaired cerebral autoregulation may predispose patients to cerebral
hypoperfusion during cardiopulmonary bypass (CPB). The purpose of this study was to …

Cerebral and tissue oximetry

J Steppan, CW Hogue Jr - Best practice & research Clinical …, 2014 - Elsevier
The use of near-infrared spectroscopy (NIRS) has been increasingly adopted in cardiac
surgery to measure regional cerebral oxygen saturation. This method takes advantage of the …

[HTML][HTML] Continuous cerebrovascular reactivity monitoring in moderate/severe traumatic brain injury: a narrative review of advances in neurocritical care

FA Zeiler, A Ercole, M Czosnyka, P Smielewski… - British journal of …, 2020 - Elsevier
Impaired cerebrovascular reactivity in adult moderate and severe traumatic brain injury (TBI)
is known to be associated with worse global outcome at 6–12 months. As technology has …