Conservative management of retinoblastoma: Challenging orthodoxy without compromising the state of metastatic grace.“Alive, with good vision and no comorbidity”

FL Munier, M Beck-Popovic, GL Chantada… - Progress in retinal and …, 2019 - Elsevier
Retinoblastoma is lethal by metastasis if left untreated, so the primary goal of therapy is to
preserve life, with ocular survival, visual preservation and quality of life as secondary aims …

Treatment of retinoblastoma in 2015: agreement and disagreement

DH Abramson, CL Shields, FL Munier… - JAMA …, 2015 - jamanetwork.com
The management of intraocular retinoblastoma is rapidly changing, and even recent reviews
on the subject are behind existing practices. The 4 authors of this report collectively …

The clinically used photosensitizer Verteporfin (VP) inhibits YAP-TEAD and human retinoblastoma cell growth in vitro without light activation

K Brodowska, A Al-Moujahed, A Marmalidou… - Experimental eye …, 2014 - Elsevier
Verteporfin (VP), a benzoporphyrin derivative, is clinically used in photodynamic therapy for
neovascular macular degeneration. Recent studies indicate that VP may inhibit growth of …

Retinoblastoma management: advances in enucleation, intravenous chemoreduction, and intra-arterial chemotherapy

CL Shields, JA Shields - Current opinion in ophthalmology, 2010 - journals.lww.com
Progress has been made in the past few years in the management of retinoblastoma with
better enucleation implants, chemoreduction-prevention of pinealoblastoma and excellent …

Ocular side effects following intravitreal injection therapy for retinoblastoma: a systematic review

SJ Smith, BD Smith, BG Mohney - British Journal of Ophthalmology, 2014 - bjo.bmj.com
Purpose To describe the ocular side effects in patients receiving intravitreal injection therapy
(IViT) for retinoblastoma. Methods PubMed (1946–present), Scopus (all years), Science …

First-line intra-arterial versus intravenous chemotherapy in unilateral sporadic group D retinoblastoma: evidence of better visual outcomes, ocular survival and shorter …

FL Munier, P Mosimann, F Puccinelli… - British Journal of …, 2017 - bjo.bmj.com
Purpose The introduction of intra-arterial chemotherapy (IAC) as salvage treatment has
improved the prognosis for eye conservation in group D retinoblastoma. The aim of this …

Current update on retinoblastoma

SK Houston, TG Murray, SQ Wolfe… - International …, 2011 - journals.lww.com
Treatment of retinoblastoma has undergone significant advancements over the past few
decades, as globe-salvaging therapies with chemoreduction and focal consolidation are …

Focal therapy in prostate cancer: modalities, findings and future considerations

U Lindner, J Trachtenberg, N Lawrentschuk - Nature Reviews Urology, 2010 - nature.com
Focal therapy is emerging as an alternative to active surveillance for the management of low-
risk prostate cancer in carefully selected patients. The aim of focal therapy is long-term …

Conservative treatment modalities in retinoblastoma

B Chawla, A Jain, R Azad - Indian Journal of Ophthalmology, 2013 - journals.lww.com
Retinoblastoma is the most common primary intraocular malignancy of childhood. A
potentially curable cancer, its treatment has improved significantly over the last few decades …

Retinoblastoma

VM Villegas, DJ Hess, A Wildner, AS Gold… - Current Opinion in …, 2013 - journals.lww.com
Progressive advances in the understanding of retinoblastoma pathogenesis continue to lead
treatment strategies. Improvements in the diagnosis and management of retinoblastoma are …