Vascular diseases are the most prevalent cause of ischemic necrosis of tissue and organ,
which even result in dysfunction and death. Vascular regeneration or artificial vascular graft …

The microvascular endothelial cell monolayer localized at the critical interface between the
blood and vessel wall has the vital functions of regulating tissue fluid balance and supplying …

The influence of psychosocial factors on the development and progression of cancer has
been a longstanding hypothesis since ancient times. In fact, epidemiological and clinical …

Epidemiological studies indicate that stress, chronic depression and lack of social support
might serve as risk factors for cancer development and progression. Recent cellular and …

Purpose: There is growing evidence that stress and other behavioral factors may affect
cancer progression and patient survival. The underlying mechanisms for this association are …

cAMP‐mediated signaling pathways regulate a multitude of important biological processes
under both physiological and pathological conditions, including diabetes, heart failure and …

Ras oncoproteins play pivotal roles in both the development and maintenance of many
tumor types. Unfortunately, these proteins are difficult to directly target using traditional …

The small GTPase Rap1 is involved in several aspects of cell adhesion, including integrin-
mediated cell adhesion and cadherin-mediated cell junction formation. Recently, several …

By linking actin dynamics to extracellular components, integrins are involved in a wide range
of cellular processes that are associated with or require cytoskeletal remodelling and cell …

A growing number of studies indicate that chronic stress can accelerate tumor growth due to
sustained sympathetic nervous system activation. Our recent findings suggest that chronic …