Primary structure of glycans by NMR spectroscopy

C Fontana, G Widmalm - Chemical Reviews, 2023 - ACS Publications
Glycans, carbohydrate molecules in the realm of biology, are present as biomedically
important glycoconjugates and a characteristic aspect is that their structures in many …

Molecular recognition insights of sialic acid glycans by distinct receptors unveiled by NMR and molecular modeling

CO Soares, AS Grosso, J Ereño-Orbea… - Frontiers in Molecular …, 2021 - frontiersin.org
All cells are decorated with a highly dense and complex structure of glycan chains, which
are mostly attached to proteins and lipids. In this context, sialic acids are a family of nine …

Glycan Shape, Motions, and Interactions Explored by NMR Spectroscopy

G Widmalm - JACS Au, 2024 - ACS Publications
Glycans in the form of oligosaccharides, polysaccharides, and glycoconjugates are
ubiquitous in nature, and their structures range from linear assemblies to highly branched …

Modeling and simulation of bacterial outer membranes with lipopolysaccharides and capsular polysaccharides

Y Gao, G Widmalm, W Im - Journal of Chemical Information and …, 2023 - ACS Publications
Capsule is one of the common virulence factors in Gram-negative bacteria protecting
pathogens from host defenses and consists of long-chain capsular polysaccharides (CPS) …

Relaxation-Assisted Magnetization Transfer Phenomena for a Sensitivity-Enhanced 2D NMR

M Novakovic, J Kim, XC Su, E Kupče… - Analytical …, 2023 - ACS Publications
2D NOESY and TOCSY play central roles in contemporary NMR. We have recently
discussed how solvent-driven exchanges can significantly enhance the sensitivity of such …

Protomer of Imipramine Captured in Cucurbit [7] uril

J Lee, H Kim, H Lee, DR Boraste, K Kim… - The Journal of Physical …, 2023 - ACS Publications
Small molecules possessing multiple proton-accessible sites are important not only to many
biological systems but also to host–guest chemistry; their protonation states are causal to …