Vascular dementia (VaD) is the second leading form of dementia after Alzheimer's disease
(AD) plaguing the elderly population. VaD is a progressive disease caused by reduced …

Bruce McEwen's discovery of receptors for corticosterone in the rat hippocampus introduced
higher brain circuits in the neuroendocrinology of stress. Subsequently, these receptors …

The glymphatic system is a brainwide CSF transport system that uses the perivascular space
for fast inflow of CSF. Arterial pulsations are a major driver of glymphatic CSF inflow, and …

Abstract Alzheimer's disease (AD), the most frequent cause of dementia, is escalating as a
global epidemic, and so far, there is neither cure nor treatment to alter its progression. The …

Introduction Cerebral small vessel disease (cSVD) is one of the most prevalent neurological
disorders. The progressive remodeling of brain microvessels due to arterial hypertension or …

The second-most common cause of dementia is vascular dementia (VaD). The majority of
VaD patients experience cognitive impairment, which is brought on by oxidative stress and …

The prevalence, morphology and pathogenesis of vascular dementia (VaD), recently termed
vascular cognitive disorder (VCD), are a matter of discussion. VaD is suggested in 8–15% of …

Background Hypertension-induced microvascular brain injury is a major vascular contributor
to cognitive impairment and dementia. We hypothesized that chronic hypoxia promotes the …

Multiple biological processes are related to cognitive impairment in older adults, but their
combined impact on cognition in midlife is not known. Using an array of measurements …

New findings on flow or drainage pathways of brain interstitial fluid and cerebrospinal fluid
have been made. The interstitial fluid flow has an effect on the passage of blood‐borne …