Abstract Purpose of Review To provide an overview and highlight recent updates in the field
of paraneoplastic neurologic disorders. Recent Findings The prevalence of paraneoplastic …

Facioscapulohumeral muscular dystrophy (FSHD) is characterised by progressive skeletal
muscle weakness and wasting. FSHD is linked to epigenetic derepression of the …

Protean immune cell abnormalities characterize different IIM subsets, reflecting the
complexity of these autoimmune conditions. A deeper understanding of B-cell and T-cell …

Besides its primary function in locomotion, skeletal muscle (SKM), which represents up to
half of human's weight, also plays a fundamental homeostatic role. Through the secretion of …

Healthy skeletal muscle undergoes repair in response to mechanically localised strains
during activities such as exercise. The ability of cells to transduce the external stimuli into a …

Research on the relationship between inflammatory myopathy and malignancy has grown
considerably within the last century. Now, the burgeoning field of inflammatory myopathy …

Objectives: Describe the histopathology of dermatomyositis. Identify the typical history and
physical exam findings associated with dermatomyositis. Review the complications of …

Objective To define the characteristic findings on MRI of skeletal muscles in patients with
dermatomyositis (DM) relative to those in patients with other idiopathic inflammatory …

Nonimmune mechanisms contribute to the pathogenesis of IIM, likely cooperating with
immune-mediated inflammation. Consistent data were released for ER stress, autophagy …

Introduction Previous work in humans has demonstrated that both innate and adaptive
immune signaling pathways contribute to the pathogenesis of idiopathic inflammatory …