Immediate early genes, memory and psychiatric disorders: focus on c-Fos, Egr1 and Arc

FT Gallo, C Katche, JF Morici, JH Medina… - Frontiers in behavioral …, 2018 - frontiersin.org
Many psychiatric disorders, despite their specific characteristics, share deficits in the
cognitive domain including executive functions, emotional control and memory. However …

Dendritic spines in depression: what we learned from animal models

H Qiao, MX Li, C Xu, HB Chen, SC An… - Neural plasticity, 2016 - Wiley Online Library
Depression, a severe psychiatric disorder, has been studied for decades, but the underlying
mechanisms still remain largely unknown. Depression is closely associated with alterations …

The role of early growth response 1 (EGR1) in brain plasticity and neuropsychiatric disorders

F Duclot, M Kabbaj - Frontiers in behavioral neuroscience, 2017 - frontiersin.org
It is now clearly established that complex interactions between genes and environment are
involved in multiple aspects of neuropsychiatric disorders, from determining an individual's …

Know thy SEFL: Fear sensitization and its relevance to stressor-related disorders

KJ Nishimura, AM Poulos, MR Drew… - … & Biobehavioral Reviews, 2022 - Elsevier
Extreme stress can cause long-lasting changes in affective behavior manifesting in
conditions such as post-traumatic stress disorder (PTSD). Understanding the biological …

Emotional modulation of learning and memory: pharmacological implications

RT LaLumiere, JL McGaugh, CK McIntyre… - Pharmacological …, 2017 - Elsevier
Memory consolidation involves the process by which newly acquired information becomes
stored in a long-lasting fashion. Evidence acquired over the past several decades …

Cognitive dysfunction in major depressive disorder. A translational review in animal models of the disease

F Darcet, AM Gardier, R Gaillard, DJ David… - Pharmaceuticals, 2016 - mdpi.com
Major Depressive Disorder (MDD) is the most common psychiatric disease, affecting millions
of people worldwide. In addition to the well-defined depressive symptoms, patients suffering …

Post-traumatic stress disorder: the relationship between the fear response and chronic stress

LY Maeng, MR Milad - Chronic Stress, 2017 - journals.sagepub.com
Post-traumatic stress disorder (PTSD) is a disabling psychiatric condition that can develop
following a physical, psychological, or sexual trauma. Despite the growing body of literature …

A critical evaluation of the activity-regulated cytoskeleton-associated protein (Arc/Arg3. 1)'s putative role in regulating dendritic plasticity, cognitive processes, and …

Y Li, AL Pehrson, JA Waller, E Dale… - Frontiers in …, 2015 - frontiersin.org
Major depressive disorder (MDD) is primarily conceptualized as a mood disorder but
cognitive dysfunction is also prevalent, and may limit the daily function of MDD patients …

[HTML][HTML] Fluoxetine and environmental enrichment similarly reverse chronic social stress-related depression-and anxiety-like behavior, but have differential effects on …

ZA Cordner, I Marshall-Thomas, GJ Boersma… - Neurobiology of …, 2021 - Elsevier
The adverse effects of stress on brain and behavior have long been known and well-studied,
with abundant evidence linking stress to, among other things, mood and anxiety disorders …

Sex differences in adult mood and in stress-induced transcriptional coherence across mesocorticolimbic circuitry

W Paden, K Barko, R Puralewski, KM Cahill… - Translational …, 2020 - nature.com
Women are approximately two times as likely to be diagnosed with major depressive
disorder (MDD) compared to men. While sex differences in MDD might be driven by …