At fertilization, the gametes endow the embryo with a genomic blueprint, the integrity of
which is affected by the age and environmental exposures of both parents. Recent studies …

BACKGROUND The concept of developmental programming suggests that the early life
environment influences offspring characteristics in later life, including the propensity to …

This paper takes a comprehensive look at the latest evidence regarding the significance of
the first 1000 days, and the biological, global, environmental and social factors that influence …

Successful pregnancy requires an appropriate communication between the mother and the
embryo. Recently, exosomes and microvesicles, both membrane-bound extracellular …

Assisted reproductive technologies (ARTs) have been proposed as a means of overcoming
the significant challenges of managing small, isolated populations of endangered species in …

A variety of evolutionary processes has led to the development of different organs to ensure
that internal fertilization occur successfully. Fallopian tubes are a particularly interesting …

Background L-arginine is considered to be one of the most versatile amino acids due to the
fact that it serves as a precursor for many important molecules in cellular physiology. When …

Epigenetic reprogramming plays a pivotal role during embryogenesis, including both
covalent and non-covalent modifications to chromatin. In this study, we investigated the role …

Recalling the evolutionary sequence of development first of gonad and subsequently of
oviducts, ovarian endocrine regulation of all known components of oviduct physiology is …

Objective To determine the composition of commercially available culture media and test
whether differences in composition are biologically relevant in a murine model. Design …