[HTML][HTML] Application of Single Cell Type-Derived Spheroids Generated by Using a Hanging Drop Culture Technique in Various In Vitro Disease Models: A Narrow …

H Ohguro, M Watanabe, T Sato, N Nishikiori, A Umetsu… - Cells, 2024 - mdpi.com
Cell culture methods are indispensable strategies for studies in biological sciences and for
drug discovery and testing. Most cell cultures have been developed using two-dimensional …

Cell‐instructive biomaterials in tissue engineering and regenerative medicine

B Adhikari, MA Stager, MD Krebs - Journal of Biomedical …, 2023 - Wiley Online Library
The field of biomaterials aims to improve regenerative outcomes or scientific understanding
for a wide range of tissue types and ailments. Biomaterials can be fabricated from natural or …

Glycosaminoglycans influence extracellular matrix of human trabecular meshwork cells cultured on 3D scaffolds

B Adhikari, MJ Osmond, MB Pantcheva… - … Science & Engineering, 2022 - ACS Publications
Glaucoma is a multifactorial progressive optic neuropathy characterized by the loss of retinal
ganglion cells leading to irreversible blindness. It is the leading cause of global irreversible …

Precision Engineering of Chondrocyte Microenvironments: Investigating the Optimal Reaction Conditions for Type B Gelatin Methacrylate Hydrogel Matrix for TC28a2 …

Q Hu, MA Torres, H Pan, SL Williams… - Journal of Functional …, 2024 - mdpi.com
Gelatin methacrylate (GelMA) is a photocrosslinkable biomaterial that has gained
widespread use in tissue engineering due to its favorable biological attributes and …

Self-generating electricity system driven by aqueous humor flow and trabecular meshwork contraction motion activated BCKa for glaucoma intraocular pressure …

R Wang, H Wei, Y Shi, C Wang, Z Yu, Y Zhang… - Materials …, 2025 - pubs.rsc.org
Primary open-angle glaucoma (POAG) is the most common form of glaucoma and the
leading cause of irreversible vision loss and blindness worldwide. Intraocular pressure (IOP) …

3D printed gelatin methacryloyl hydrogels for perfusion culture of human trabecular meshwork cells and glaucoma studies

B Adhikari, P Barakoti, MB Pantcheva… - Biotechnology and …, 2025 - Wiley Online Library
Glaucoma, a progressive eye disease leading to irreversible blindness, currently affects over
70 million people globally. Elevated intraocular pressure (IOP) is implicated in its …

[HTML][HTML] ECM biomaterials for modeling of outflow cell biology in health and disease

S Ghosh, S Herberg - Biomaterials and Biosystems, 2024 - Elsevier
This review highlights the importance of extracellular matrix (ECM) biomaterials in
understanding the biology of human trabecular meshwork (TM) and Schlemm's canal (SC) …

Development of Cell Culture Platforms for Study of Trabecular Meshwork Cells and Glaucoma Development

KI Youn, JW Lee, Y Song, SY Lee, KH Song - Tissue Engineering and …, 2024 - Springer
Background: Various cell culture platforms that could display native environmental cue-
mimicking stimuli were developed, and effects of environmental cues on cell behaviors were …

Design and Characterization of Cell-Interactive Biomaterials in Orthopedics and Wound Healing

MA Stager - 2023 - search.proquest.com
The field of biomaterials encompasses an area of medical research that focuses on the
design, characterization, and implementation of materials which interact with the human …

[PDF][PDF] Utilising glaucomatous extracellular matrix substrates and novel biomimetic 3D polymer scaffolds to study trabecular meshwork (TM) cells and TM progenitors.

O Kingston - 2024 - livrepository.liverpool.ac.uk
Primary open-angle glaucoma (POAG) is the leading cause of irreversible blindness
worldwide. Current methods of treatment aim to reduce intraocular pressure (IOP), which is …