The nuclear factor kappa B (NFκB) family of transcription factors is a key regulator of immune
development, immune responses, inflammation, and cancer. The NFκB signaling system …

The NF-κB family of inducible transcription factors is activated in response to a variety of
stimuli. Amongst the best-characterized inducers of NF-κB are members of the TNF family of …

Abstract The NF-κB (Nuclear Factor kappa B) transcription factor plays crucial roles in the
regulation of numerous biological processes including development of the immune system …

Elevated rates of reactive oxygen species (ROS) have been detected in almost all cancers,
where they promote many aspects of tumour development and progression. However …

Hepatic cirrhosis and hepatocellular carcinoma (HCC) are the most common causes of
death in patients with chronic liver disease. Chronic liver injury of virtually any etiology …

The IκB kinase (IKK) complex is the signal integration hub for NF‐κB activation. Composed
of two serine‐threonine kinases (IKK α and IKK β) and the regulatory subunit NEMO (also …

Stimulation of TNFR1 by TNFα can promote three distinct alternative mechanisms of cell
death: necroptosis, RIPK1-independent and-dependent apoptosis. How cells decide which …

Nuclear factor κB (NF-κB) is an antiapoptotic transcription factor. We show that the
antiapoptotic actions of NF-κB are mediated by hydrogen sulfide (H 2 S) synthesized by …

The NF-κB family of transcription factors has an essential role in inflammation and innate
immunity. Furthermore, NF-κB is increasingly recognized as a crucial player in many steps of …

The transcription factor NF-κB has served as a standard for inducible transcription factors for
more than 20 years. The numerous stimuli that activate NF-κB, and the large number of …