Development of in silico models to predict viscosity and mouse clearance using a comprehensive analytical data set collected on 83 scaffold-consistent monoclonal …
M Mock, AW Jacobitz, CJ Langmead, A Sudom, D Yoo… - MAbs, 2023 - Taylor & Francis
Biologic drug discovery pipelines are designed to deliver protein therapeutics that have
exquisite functional potency and selectivity while also manifesting biophysical …
exquisite functional potency and selectivity while also manifesting biophysical …
LAP: Liability Antibody Profiler by sequence & structural mapping of natural and therapeutic antibodies
T Satława, M Tarkowski, S Wróbel… - PLOS Computational …, 2024 - journals.plos.org
Antibody-based therapeutics must not undergo chemical modifications that would impair
their efficacy or hinder their developability. A commonly used technique to de-risk lead …
their efficacy or hinder their developability. A commonly used technique to de-risk lead …