Type IV pilus structure and bacterial pathogenicity

L Craig, ME Pique, JA Tainer - Nature Reviews Microbiology, 2004 - nature.com
Type IV pili are remarkably strong, flexible filaments with varied roles in bacterial
pathogenicity. All Gram-negative bacterial surfaces have type IV pili, which are polymeric …

DNA uptake in bacteria

D Dubnau - Annual Reviews in Microbiology, 1999 - annualreviews.org
▪ Abstract Natural competence is widespread among bacterial species. The mechanism of
DNA uptake in both gram-positive and gram-negative bacteria is reviewed. The …

Type IV pili in Gram-positive bacteria

S Melville, L Craig - Microbiology and molecular biology reviews, 2013 - Am Soc Microbiol
SUMMARY Type IV pili (T4P) are surface-exposed fibers that mediate many functions in
bacteria, including locomotion, adherence to host cells, DNA uptake (competence), and …

Type IV pili: paradoxes in form and function

L Craig, J Li - Current opinion in structural biology, 2008 - Elsevier
Type IV pili are filaments on the surfaces of many Gram-negative bacteria that mediate an
extraordinary array of functions, including adhesion, motility, microcolony formation and …

[HTML][HTML] Epidemiology and pathogenesis of Neisseria meningitidis

YL Tzeng, DS Stephens - Microbes and infection, 2000 - Elsevier
Neisseria meningitidis, an exclusive pathogen of humans, remains the leading worldwide
cause of meningitis and fatal sepsis, usually in otherwise healthy individuals. In recent …

PilT mutations lead to simultaneous defects in competence for natural transformation and twitching motility in piliated Neisseria gonorrhoeae

M Wolfgang, P Lauer, HS Park, L Brossay… - Molecular …, 1998 - Wiley Online Library
Neisseria gonorrhoeae, the Gram‐negative aetiological agent of gonorrhoea, is one of many
mucosal pathogens of man that expresses competence for natural transformation …

[HTML][HTML] A review on pilus assembly mechanisms in Gram-positive and Gram-negative bacteria

T Shanmugasundarasamy, DK Govindarajan… - The Cell Surface, 2022 - Elsevier
The surface of Gram-positive and Gram-negative bacteria contains long hair-like
proteinaceous protrusion known as pili or fimbriae. Historically, pilin proteins were …

[HTML][HTML] Components and dynamics of fiber formation define a ubiquitous biogenesis pathway for bacterial pili

M Wolfgang, JPM van Putten, SF Hayes… - The EMBO …, 2000 - embopress.org
Type IV pili (Tfp) are a unique class of multifunctional surface organelles in Gram‐negative
bacteria, which play important roles in prokaryotic cell biology. Although components of the …

Surface organelles assembled by secretion systems of Gram-negative bacteria: diversity in structure and function

DG Thanassi, JB Bliska… - FEMS microbiology …, 2012 - academic.oup.com
Gram-negative bacteria express a wide variety of organelles on their cell surface. These
surface structures may be the end products of secretion systems, such as the hair-like fibers …

[HTML][HTML] Commensal Neisseria kill Neisseria gonorrhoeae through a DNA-dependent mechanism

WJ Kim, D Higashi, M Goytia, MA Rendón… - Cell host & …, 2019 - cell.com
The mucosa is colonized with commensal Neisseria. Some of these niches are sites of
infection for the STD pathogen Neisseria gonorrhoeae (Ngo). Given the antagonistic …