The assembly of ribosomal subunits is a highly orchestrated process that involves a huge
cohort of accessory factors. Most eukaryotic ribosome biogenesis factors were first identified …

Ribosomes, which synthesize the proteins of a cell, comprise ribosomal RNA and ribosomal
proteins, which coassemble hierarchically during a process termed ribosome biogenesis …

The essential cellular process of ribosome biogenesis is at the nexus of various signalling
pathways that coordinate protein synthesis with cellular growth and proliferation. The fact …

Production of small ribosomal subunits initially requires the formation of a 90 S precursor
followed by an enigmatic process of restructuring into the primordial pre-40 S subunit. We …

Abstract The transcription of 18S, 5.8 S, and 18S rRNA genes (45S rDNA), cotranscriptional
processing of pre-rRNA, and assembly of mature rRNA with ribosomal proteins are the …

The 90S preribosomal particle is required for the production of the 18S rRNA from a pre-
rRNA precursor. Despite the identification of the protein components of this particle, its …

Efficient ribosome biogenesis requires coordination of a highly complex series of events.
Early events include pre-RNA transcription, processing, and modification. Analysis in yeast …

The assembly and maturation of box C/D snoRNPs, factors essential for ribosome
biogenesis, occur in the nucleoplasm. To investigate this process, we have analyzed non …

EBP1 was identified as a protein that interacts with the ErbB-3 receptor and possibly
contributes to transducing growth regulatory signals. The existence of EBP1 homologs …

Eukaryotic ribosome biogenesis involves RNA folding and processing that depend on
assembly factors and small nucleolar RNAs (snoRNAs). The 90S (SSU-processome) is the …