The isolation-biological activities (2014–2022), bio, semi, total synthesis (1978–2022) and SAR studies of a potential naturally engineered scaffold aristolactam

MC Reddy, A Dey, M Jeganmohan… - New Journal of Chemistry, 2023 - pubs.rsc.org
Aristolactams are a small group of aporphinoid alkaloids containing the phenanthrene
chromophore that were first isolated from Aristolochia argentina (Aristolochiaceae), which is …

Goniothalamin-related Styryl lactones: Isolation, synthesis, biological activity and mode of action

RA Pilli, I de Toledo, MA Meirelles… - Current Medicinal …, 2019 - ingentaconnect.com
This review covers the chemistry and biological aspects of goniothalamin-related styryl
lactones isolated from natural sources. This family of secondary metabolites has been …

In Silico and in Vitro Evaluation of Alkaloids from Goniothalamus elegans Ast. for Breast Cancer Treatment

LTT Tran, NYT Dang, NT Nguyen Le… - Natural Product …, 2022 - journals.sagepub.com
Breast cancer is the leading cause of cancer mortality in women. In this study, liriodenine
and lysicamine from Goniothalamus elegans Ast. were investigated for their anti-breast …

Phytochemicals Derived from Goniothalamus elegans Ast Exhibit Anticancer Activity by Inhibiting Epidermal Growth Factor Receptor

LTT Tran, LHD Pham, NYT Dang… - Natural Product …, 2022 - journals.sagepub.com
Cancer is a major health burden and a leading cause of death worldwide, with numerous
new molecules being studied and developed as therapeutic agents. In this study, the …

Comparative Analysis of Aristolochic Acids in Aristolochia Medicinal Herbs and Evaluation of Their Toxicities

SH Zhang, Y Wang, J Yang, DD Zhang, YL Wang… - Toxins, 2022 - mdpi.com
Aristolochic acids (AAs) are a group of nitrophenanthrene carboxylic acids present in many
medicinal herbs of the Aristolochia genus that may cause irreversible hepatotoxicity …

Isolation, structural elucidation, and cytotoxic activity investigation of novel styryl-lactone derivatives from Goniothalamus elegans: in vitro and in silico studies

TK Nguyen, LTT Tran, TT Tan, PTV Pham… - RSC …, 2023 - pubs.rsc.org
Two styryl-lactone derivatives (1 and 2) were isolated from the aerial parts of Goniothalamus
elegans. Compound 1 is a newly discovered natural product, and compound 2 is reported in …

Goniolanceolatins A–H, Cytotoxic Bis-styryllactones from Goniothalamus lanceolatus

NV Bihud, NE Rasol, S Imran, K Awang… - Journal of natural …, 2019 - ACS Publications
Eight new bis-styryllactones, goniolanceolatins A–H (1–8), possessing a rare α, β-
unsaturated δ-lactone moiety with a (6 S)-configuration, were isolated from the CH2Cl2 …

Alkaloids and styryllactones from Goniothalamus cheliensis

W Jaidee, RJ Andersen, BO Patrick, SG Pyne… - Phytochemistry, 2019 - Elsevier
Eight previously undescribed compounds, including four alkaloids and five styryllactones
together with 36 known compounds were isolated from the twig and leaf extracts of …

Light‐Regulated Release of Entrapped Drugs from Photoresponsive Gold Nanoparticles

K Sreejivungsa, N Suchaichit… - Journal of …, 2016 - Wiley Online Library
Release of a payload in a spatiotemporal fashion has a substantial impact on increasing
therapeutic efficacy. In this work, a novel monolayer of gold nanoparticles (AuNPs) featuring …

In vitro antiplasmodial and cytotoxicity activities of crude extracts and major compounds from Goniothalamus lanceolatus

FA Kaharudin, RM Zohdi, SM Mukhtar, HM Sidek… - Journal of …, 2020 - Elsevier
Ethnopharmacological relevance Malaria, a devastating infectious disease which was
initially recognized as episodic fever, is caused by parasitic protozoan of the genus …