High-throughput methods in the discovery and study of biomaterials and materiobiology
The complex interaction of cells with biomaterials (ie, materiobiology) plays an increasingly
pivotal role in the development of novel implants, biomedical devices, and tissue …
pivotal role in the development of novel implants, biomedical devices, and tissue …
Integrating biosensors in organs-on-chip devices: A perspective on current strategies to monitor microphysiological systems
Organs-on-chip (OoC), often referred to as microphysiological systems (MPS), are advanced
in vitro tools able to replicate essential functions of human organs. Owing to their …
in vitro tools able to replicate essential functions of human organs. Owing to their …
Beating heart on a chip: a novel microfluidic platform to generate functional 3D cardiac microtissues
A Marsano, C Conficconi, M Lemme, P Occhetta… - Lab on a Chip, 2016 - pubs.rsc.org
In the past few years, microfluidic-based technology has developed microscale models
recapitulating key physical and biological cues typical of the native myocardium. However …
recapitulating key physical and biological cues typical of the native myocardium. However …
Microfluidic platforms for mechanobiology
Mechanotransduction has been a topic of considerable interest since early studies
demonstrated a link between mechanical force and biological response. Until recently …
demonstrated a link between mechanical force and biological response. Until recently …
Microfluidics for neuronal cell and circuit engineering
The widespread adoption of microfluidic devices among the neuroscience and neurobiology
communities has enabled addressing a broad range of questions at the molecular, cellular …
communities has enabled addressing a broad range of questions at the molecular, cellular …
Controlled electromechanical cell stimulation on-a-chip
Stem cell research has yielded promising advances in regenerative medicine, but standard
assays generally lack the ability to combine different cell stimulations with rapid sample …
assays generally lack the ability to combine different cell stimulations with rapid sample …
A directional 3D neurite outgrowth model for studying motor axon biology and disease
XM Spijkers, S Pasteuning-Vuhman, JC Dorleijn… - Scientific reports, 2021 - nature.com
We report a method to generate a 3D motor neuron model with segregated and directed
axonal outgrowth. iPSC-derived motor neurons are cultured in extracellular matrix gel in a …
axonal outgrowth. iPSC-derived motor neurons are cultured in extracellular matrix gel in a …
Advances in ex vivo models and lab-on-a-chip devices for neural tissue engineering
The technologies related to ex vivo models and lab-on-a-chip devices for studying the
regeneration of brain, spinal cord, and peripheral nerve tissues are essential tools for neural …
regeneration of brain, spinal cord, and peripheral nerve tissues are essential tools for neural …
Central nervous system and its disease models on a chip
Technologies for microfluidics and biological microelectromechanical systems have been
rapidly progressing over the past decade, enabling the development of unique …
rapidly progressing over the past decade, enabling the development of unique …
Bendable polymer electrolyte fuel cell using highly flexible Ag nanowire percolation network current collectors
This study reports a polymer electrolyte fuel cell based on polydimethylsiloxane coated with
a flexible current-collecting layer of Ag nanowire percolation networks. The reactive area of …
a flexible current-collecting layer of Ag nanowire percolation networks. The reactive area of …