Tumor cells do not exist in isolation in vivo, and carcinogenesis depends on the surrounding
tumor microenvironment (TME), composed of a myriad of cell types and biophysical and …

Gallbladder cancer (GBC) is the most common cancer of the biliary tract, characterized by a
very poor prognosis when diagnosed at advanced stages owing to its aggressive behaviour …

Epithelial–mesenchymal transition (EMT) or mesenchymal–epithelial transition (MET) plays
critical roles in cancer metastasis. Recent studies, especially those based on single‐cell …

The genetic circuits that allow cancer cells to evade immune killing via epithelial
mesenchymal plasticity remain poorly understood. Here, we showed that mesenchymal-like …

Epithelial–mesenchymal transition (EMT) is a fundamental process that occurs during
embryogenesis and tissue repair. However, EMT can be hijacked by malignant cells, where …

In the process of cancer EMT, some subgroups of cancer cells simultaneously exhibit both
mesenchymal and epithelial characteristics, a phenomenon termed partial EMT (pEMT) …

The tumor microenvironment (TME) corresponds to a complex and dynamic interconnection
between the extracellular matrix and malignant cells and their surrounding stroma …

Head and neck squamous cell carcinomas (HNSCCs) are the eighth most common cancers
worldwide. While promising new therapies are emerging, cisplatin-based chemotherapy …

Transforming growth factor β (TGF-β) increases epithelial cancer cell migration and
metastasis by inducing epithelial-mesenchymal transition (EMT). TGF-β also inhibits cell …

Immune checkpoint blockade (ICB) approaches have changed the therapeutic landscape for
many tumor types. However, half of cutaneous squamous cell carcinoma (cSCC) patients …