Lipid droplets are storage organelles at the centre of lipid and energy homeostasis. They
have a unique architecture consisting of a hydrophobic core of neutral lipids, which is …

Our knowledge of inter-organellar communication has grown exponentially in recent years.
This review focuses on the interactions that cytoplasmic lipid droplets have with other …

Lipid incorporation from endoplasmic reticulum (ER) to lipid droplet (LD) is important in
controlling LD growth and intracellular lipid homeostasis. However, the molecular link …

Pathways localizing proteins to their sites of action are essential for eukaryotic cell
organization and function. Although mechanisms of protein targeting to many organelles …

Dynamic interaction between lipid droplets (LDs) and mitochondria controls the mobilization
of long-chain fatty acids (LCFAs) from LDs for mitochondrial β-oxidation in skeletal muscle in …

Tumor progression involves invasion, migration, metabolism, autophagy, exosome
secretion, and drug resistance. Cargos transported by membrane vesicle trafficking underlie …

Lipids are essential components for life. Their various structural and physical properties
influence diverse cellular processes and, thereby, human health. Lipids are not genetically …

Lipid droplets (LDs) are ubiquitous cellular organelles for lipid storage which are composed
of a neutral lipid core bounded by a protein decorated phospholipid monolayer. Although …

Proteomic studies have revealed many potential functions of cytoplasmic lipid droplets, and
recent activity has confirmed that these bona fide organelles are central not only for lipid …

Cooperation between organelles is essential to maintain the normal operation of the cell. A
lipid droplet (LD), a dynamic organelle, is specialized in lipid storage and can interact …