Health benefits and side effects of short-chain fatty acids

RG Xiong, DD Zhou, SX Wu, SY Huang, A Saimaiti… - Foods, 2022 - mdpi.com
The gut microbiota and their metabolites could play an important role in health and diseases
of human beings. Short-chain fatty acids (SCFAs) are mainly produced by gut microbiome …

The gut microbiome and hypertension

JA O'Donnell, T Zheng, G Meric… - Nature Reviews …, 2023 - nature.com
A large body of evidence has emerged in the past decade supporting a role for the gut
microbiome in the regulation of blood pressure. The field has moved from association to …

Short-chain fatty acids and their association with signalling pathways in inflammation, glucose and lipid metabolism

J He, P Zhang, L Shen, L Niu, Y Tan, L Chen… - International journal of …, 2020 - mdpi.com
Short-chain fatty acids (SCFAs), particularly acetate, propionate and butyrate, are mainly
produced by anaerobic fermentation of gut microbes. SCFAs play an important role in …

Short-chain fatty acids in diseases

D Zhang, YP Jian, YN Zhang, Y Li, LT Gu… - Cell Communication and …, 2023 - Springer
Short-chain fatty acids (SCFAs) are the main metabolites produced by bacterial fermentation
of dietary fibre in the gastrointestinal tract. The absorption of SCFAs is mediated by substrate …

Propionate attenuates atherosclerosis by immune-dependent regulation of intestinal cholesterol metabolism

A Haghikia, F Zimmermann, P Schumann… - European heart …, 2022 - academic.oup.com
Aims Atherosclerotic cardiovascular disease (ACVD) is a major cause of mortality and
morbidity worldwide, and increased low-density lipoproteins (LDLs) play a critical role in …

Short-chain fatty acid metabolism and multiple effects on cardiovascular diseases

T Hu, Q Wu, Q Yao, K Jiang, J Yu, Q Tang - Ageing research reviews, 2022 - Elsevier
Cardiovascular diseases (CVDs) are the leading cause of mortality worldwide, and fatty acid
metabolism has been well studied. Short-chain fatty acids (SCFAs) have been less …

Gut microbiota and their metabolites in stroke: a double-edged sword

A Peh, JA O'Donnell, BRS Broughton, FZ Marques - Stroke, 2022 - Am Heart Assoc
Besides damaging the brain, stroke causes systemic changes, including to the
gastrointestinal system. A growing body of evidence supports the role of the gut and its …

Gut dysbiosis promotes preeclampsia by regulating macrophages and trophoblasts

J Jin, L Gao, X Zou, Y Zhang, Z Zheng… - Circulation …, 2022 - Am Heart Assoc
Background: Preeclampsia is one of the leading causes of maternal and perinatal morbidity
and is characterized by hypertension, inflammation, and placental dysfunction. Gut …

[HTML][HTML] Gut microbiota dysbiosis, oxidative stress, inflammation, and epigenetic alterations in metabolic diseases

H Mostafavi Abdolmaleky, JR Zhou - Antioxidants, 2024 - mdpi.com
Gut dysbiosis, resulting from an imbalance in the gut microbiome, can induce excessive
production of reactive oxygen species (ROS), leading to inflammation, DNA damage …

Recent advances in modulation of cardiovascular diseases by the gut microbiota

SK Masenga, B Hamooya, J Hangoma… - Journal of Human …, 2022 - nature.com
The gut microbiota has recently gained attention due to its association with cardiovascular
health, cancers, gastrointestinal disorders, and non-communicable diseases. One critical …