summary Great progress continues to be made in our understanding of the multiple facets of
osteoarthritis (OA) biology. Here, we review the major advances in this field and progress …

Objective Osteoarthritis (OA) is a complex disease involving contributions from both local
joint tissues and systemic sources. Patient characteristics, encompassing sociodemographic …

Fibroblasts are important regulators of inflammation, but whether fibroblasts change
phenotype during resolution of inflammation is not clear. Here we use positron emission …

Osteoarthritis (OA) affects multiple tissues in the knee joint, including the synovium and intra-
articular adipose tissue (IAAT) that are attached to each other. However, whether these two …

The identity and origin of the stem/progenitor cells for adult joint cartilage repair remain
unknown, impeding therapeutic development. Simulating the common therapeutic modality …

The synovium, a thin layer of tissue that is adjacent to the joints and secretes synovial fluid,
undergoes changes in aging that contribute to intense shoulder pain and other joint …

Osteoarthritis (OA) management remains challenging because of its intricate pathogenesis.
Intra‐articular injections of drugs, such as glucocorticoids and hyaluronic acid (HA), have …

Objective Obesity increases osteoarthritis (OA) risk due to adipose tissue dysfunction with
associated metabolic syndrome and excess weight. Lipodystrophy syndromes exhibit …

Osteoarthritis (OA) is a significant global burden, affecting more than half a billion people
across the world. It is characterized by degeneration and loss of articular cartilage, synovial …

Highly interesting findings revealing mechanisms of RASF activation and altered functions
have been published, RASF subsets further characterized, and interactions with cell types …