BACKGROUND Germ cell depletion caused by chemical or physical toxicity, disease or
genetic predisposition can occur at any age. Although semen cryopreservation is the first …

BACKGROUND Childhood cancer incidence and survivorship are both on the rise.
However, many lifesaving treatments threaten the prepubertal testis. Cryopreservation of …

STUDY QUESTION Does vitrification of human immature testicular tissue (ITT) have
potential benefits for future fertility preservation? Does vitrification of human ITT have …

STUDY QUESTION Is there a better alternative to the conventional cryopreservation
protocols for human testicular tissue banking? SUMMARY ANSWER Uncontrolled slow …

Fertility preservation in prepubertal boys facing gonadotoxic treatment is still at the
experimental stage. Nevertheless cryopreservation of immature testicular tissue (ITT) …

OBJECTIVE: To assess vitrification of prepubertal human testicular tissue in vitro. DESIGN:
Case report. SETTING: Academic research unit. PATIENT (S): Two patients (6 and 12 years …

The broad conceptualization of fertility preservation and restoration has become already a
major concern in the modern western world since a large number of individuals often face it …

Traditional therapeutic interventions aim to restore male fertile potential or preserve sperm
viability in severe cases, such as semen cryopreservation, testicular tissue, germ cell …

Cryopreservation of immature testicular tissues is essential for increasing the possibilities of
offspring generation by testicular xenografting for agricultural or medical purposes …

The ability to spur growth of early stage gametic cells recovered from neonates could lead to
significant advances in rescuing the genomes of rare genotypes or endangered species that …