Peptide-based gene delivery vectors

Z Kang, Q Meng, K Liu - Journal of materials chemistry B, 2019 - pubs.rsc.org
Gene therapy as a strategy for disease treatment requires safe and efficient gene delivery
systems that encapsulate nucleic acids and deliver them to effective sites in the cell. Due to …

Amphiphilic self-assembly peptides: Rational strategies to design and delivery for drugs in biomedical applications

C Zhao, H Chen, F Wang, X Zhang - Colloids and Surfaces B: Biointerfaces, 2021 - Elsevier
Amphiphilic self-assembling peptides are widely used in tissue and cell engineering,
antimicrobials, drug-delivery systems and other biomedical fields due to their good …

Hydrophobic control of the bioactivity and cytotoxicity of de novo-designed antimicrobial peptides

H Gong, J Zhang, X Hu, Z Li, K Fa, H Liu… - … applied materials & …, 2019 - ACS Publications
Antimicrobial peptides (AMPs) can target bacterial membranes and kill bacteria through
membrane structural damage and cytoplasmic leakage. A group of surfactant-like cationic …

Biomaterial‐interrelated bacterial sweeper: simplified self‐assembled octapeptides with double‐layered Trp zipper induces membrane destabilization and bacterial …

Y Fang, Y Zhu, L Li, Z Lai, N Dong, A Shan - Small Methods, 2021 - Wiley Online Library
Abstract Treatment of microbial‐associated infections continues to be hampered by impaired
antibacterial efficiency and the variability in nanomedicines. Herein, an octapeptide library …

Unnatural amino acids: Promising implications for the development of new antimicrobial peptides

X Wang, X Yang, Q Wang, D Meng - Critical Reviews in …, 2023 - Taylor & Francis
The increasing incidence and rapid spread of bacterial resistance to conventional antibiotics
are a serious global threat to public health, highlighting the need to develop new …

The best peptidomimetic strategies to undercover antibacterial peptides

JI Lachowicz, K Szczepski, A Scano, C Casu… - International journal of …, 2020 - mdpi.com
Health-care systems that develop rapidly and efficiently may increase the lifespan of
humans. Nevertheless, the older population is more fragile, and is at an increased risk of …

Hydrophobic-hydrophilic alternation: an effective pattern to de novo designed antimicrobial peptides

Q Cheng, P Zeng - Current Pharmaceutical Design, 2022 - benthamdirect.com
The antimicrobial peptide (AMP) is a class of molecules that are active against a variety of
microorganisms, from bacterial and cancer cells to fungi. Most AMPs are natural products, as …

Structural characteristics of a low molecular weight velvet antler protein and the anti-tumor activity on S180 tumor-bearing mice

T Cao, H An, R Ma, K Dai, H Ji, A Liu, J Zhou - Bioorganic Chemistry, 2023 - Elsevier
Velvet antler is a traditional Chinese medicine with various pharmacological values, which is
an important raw material for traditional Chinese medicinal wine. Nevertheless, the chemical …

Weight assignment method for multiple attribute decision making with dissimilarity and conflict of belief distributions

M Zhou, YW Chen, XB Liu, BY Cheng… - Computers & Industrial …, 2020 - Elsevier
Belief distribution (BD) is the scheme of representing uncertain and imprecise subjective
assessment in the evidential reasoning methodology. In a multiple attribute decision making …

Alternating Cationic‐Hydrophobic Peptide/Peptoid Hybrids: Influence of Hydrophobicity on Antibacterial Activity and Cell Selectivity

N Frederiksen, PR Hansen, D Zabicka… - …, 2020 - Wiley Online Library
The influence of hydrophobicity on antibacterial activity versus the effect on the viability of
mammalian cells for peptide/peptoid hybrids was examined for oligomers based on the …