Do TUNEL and other apoptosis assays detect cell death in preclinical studies?
R Mirzayans, D Murray - International Journal of Molecular Sciences, 2020 - mdpi.com
The terminal deoxynucleotidyl transferase-mediated dUTP nick end labeling (TUNEL) assay
detects DNA breakage by labeling the free 3ʹ-hydroxyl termini. Given that genomic DNA …
detects DNA breakage by labeling the free 3ʹ-hydroxyl termini. Given that genomic DNA …
A local water molecular-heating strategy for near-infrared long-lifetime imaging-guided photothermal therapy of glioblastoma
Owing to the strong absorption of water in the near-infrared (NIR) region near 1.0 μm, this
wavelength is considered unsuitable as an imaging and analytical signal in biological …
wavelength is considered unsuitable as an imaging and analytical signal in biological …
[HTML][HTML] Age-related hearing loss: prevention of threshold declines, cell loss and apoptosis in spiral ganglion neurons
RD Frisina, B Ding, X Zhu, JP Walton - Aging (Albany NY), 2016 - ncbi.nlm.nih.gov
Age-related hearing loss (ARHL)-presbycusis-is the most prevalent neurodegenerative
disease and number one communication disorder of our aged population; and affects …
disease and number one communication disorder of our aged population; and affects …
Conjugated polymers as a new class of dual-mode matrices for MALDI mass spectrometry and imaging
Matrix-assisted laser desorption/ionization mass spectrometry (MALDI MS) and MALDI MS
imaging are ubiquitous analytical methods in medical, pharmaceutical, biological, and …
imaging are ubiquitous analytical methods in medical, pharmaceutical, biological, and …
[HTML][HTML] Utilization of DNA double-strand breaks for biodosimetry of ionizing radiation exposure
A Bushmanov, N Vorobyeva, D Molodtsova… - Environmental …, 2022 - Elsevier
Abstract Analysis of DNA double-strand breaks (DSBs) is an important novel tool to estimate
the biological effects of ionizing radiation. Despite the large number of developed methods …
the biological effects of ionizing radiation. Despite the large number of developed methods …
Inhibition of DAMP actions in the tumoral microenvironment using lactoferrin-glycyrrhizin conjugate for glioblastoma therapy
Background High-mobility group box-1 (HMGB1) released from the tumor microenvironment
plays a pivotal role in the tumor progression. HMGB1 serves as a damaged-associated …
plays a pivotal role in the tumor progression. HMGB1 serves as a damaged-associated …
Parthenolide Selectively Sensitizes Prostate Tumor Tissue to Radiotherapy while Protecting Healthy Tissues In Vivo
Radiotherapy is widely used in cancer treatment, however the benefits can be limited by
radiation-induced damage to neighboring normal tissues. Parthenolide (PTL) exhibits anti …
radiation-induced damage to neighboring normal tissues. Parthenolide (PTL) exhibits anti …
Regulated cell death in cyanobacteria: Evidences, classification, and significances
J Li, L Song, J Li - Cyanobacterial Physiology, 2022 - Elsevier
Cyanobacteria, the most ancient prokaryotic organisms, are still thriving and dominating in
many marine and freshwater ecosystems. The death of cyanobacteria plays a great role in …
many marine and freshwater ecosystems. The death of cyanobacteria plays a great role in …
Inhibition of DAMP actions in the tumoral microenvironment using lactoferrin-glycyrrhizin nanoconjugate for glioblastoma therapy
HS Kim, SC Park, HJ Kim, DY Lee - 2023 - researchsquare.com
Background High-mobility group box-1 (HMGB1) released from the tumor microenvironment
plays a pivotal role in the tumor progression. HMGB1 serves as a damaged-associated …
plays a pivotal role in the tumor progression. HMGB1 serves as a damaged-associated …
[HTML][HTML] 长链非编码RNA 在食管癌中的研究进展
张丹， 侯小丽， 吴博， 李丹丹 - 世界华人消化杂志, 2015 - wjgnet.com
长链非编码RNA (long non-coding RNA, lncRNA) 是长度> 200 nt 的一类无蛋白质编码功能的
RNA. 研究表明lncRNA 可在多个水平参与基因表达调控, 影响细胞增殖, 分化, 代谢和凋亡 …
RNA. 研究表明lncRNA 可在多个水平参与基因表达调控, 影响细胞增殖, 分化, 代谢和凋亡 …