Osteoarthritis is a highly prevalent disease particularly in subjects over 65 years of age
worldwide. While in the past it was considered a mere consequence of cartilage degradation …

The immune system is the central regulator of tissue homeostasis, ensuring tissue
regeneration and protection against both pathogens and the neoformation of cancer cells. Its …

Astaxanthin (AX), a lipid-soluble pigment belonging to the xanthophyll carotenoids family,
has recently garnered significant attention due to its unique physical properties, biochemical …

Understanding the causality of the post-traumatic osteoarthritis (PTOA) disease process of
the knee joint is important for diagnosing early disease and developing new and effective …

Osteoarthritis (OA) is currently the most widespread musculoskeletal condition and primarily
affects weight-bearing joints such as the knees and hips. Importantly, knee OA remains a …

Aging is an inevitable and gradually progressive process affecting all organs and systems.
The musculoskeletal system makes no exception, elderly exhibit an increased risk of …

Vitamin K is a multifunctional micronutrient implicated in age-related diseases such as
cardiovascular diseases, osteoarthritis and osteoporosis. Although vitamin K-dependent …

Inflammation is a key mechanism for the clearance of infective agents and other
inflammatory triggers and is pivotal for the repairing processes of the affected tissues …

An implant is a device for replacing a damaged or deformed joint, bone, or cartilage.
Considering the aging population and developing culture of active lifestyles, orthopedic and …

Aging and age-related changes impact the quality of life (QOL) in elderly with a decline in
movement, cognitive abilities and increased vulnerability towards age-related diseases …