Endothelial dysfunction in neuroprogressive disorders—causes and suggested treatments

G Morris, BK Puri, L Olive, A Carvalho, M Berk… - BMC medicine, 2020 - Springer
Background Potential routes whereby systemic inflammation, oxidative stress and
mitochondrial dysfunction may drive the development of endothelial dysfunction and …

Blood-brain barrier dysfunction in bipolar disorder: molecular mechanisms and clinical implications

NO Zhao, N Topolski, M Tusconi, EM Salarda… - Brain, Behavior, & …, 2022 - Elsevier
Bipolar disorder (BD) is a severe psychiatric disorder affecting approximately 1–3% of the
population and characterized by a chronic and recurrent course of debilitating symptoms. An …

[HTML][HTML] Endothelial cell autophagy in the context of disease development

BA Marzoog - Anatomy & Cell Biology, 2023 - synapse.koreamed.org
Endothelial cells (EC) are the anatomical boundaries between the intravascular and
extravascular space. Damage to ECs is catastrophic and induces endothelial cell …

From spreading depolarization to blood–brain barrier dysfunction: navigating traumatic brain injury for novel diagnosis and therapy

G van Hameren, R Aboghazleh, E Parker… - Nature Reviews …, 2024 - nature.com
Considerable strides in medical interventions during the acute phase of traumatic brain
injury (TBI) have brought improved overall survival rates. However, following TBI, people …

[HTML][HTML] Coronary artery disease in patients with severe mental illness

BT To, R Roy, N Melikian, FP Gaughran… - Interventional …, 2023 - ncbi.nlm.nih.gov
Severe mental illnesses (SMI), such as schizophrenia and bipolar disorder, are associated
with a decrease in life expectancy of up to two decades compared with the general …

[HTML][HTML] Association of intron 4 VNTR polymorphism in the NOS3 gene with rapid cycling and treatment resistance in bipolar disorder: a case-control study

HM Aytac, M Pehlivan, Y Oyaci, S Pehlivan - Neurosciences Journal, 2022 - nsj.org.sa
Objective: To evaluate the relationship between patients' clinical parameters, especially
clinical specifiers, and the intron 4 VNTR variant of the endothelial nitric oxide synthase …

Endocan: A novel biomarker of endothelial dysfunction in depression?

E Şahan, EM Güler, A Tangılntız, İ Kırpınar - Journal of Psychiatric …, 2023 - Elsevier
Endocan is a proteoglycan secreted from endothelium upon endothelial damage. Since
depression is associated with higher inflammation and oxidative stress to the vascular …

[PDF][PDF] Oxidative metabolism and urotensin-II levels among bipolar disorder patients in a manic episode

B Demir, G Alpak - Medicine, 2019 - manage.effectpublishing.com
According to the previous studies, it has been noted many times that oxidative balance is
disrupted in bipolar disorder. However, we did not found any research investigating the …

Prepubertal ve Postpubertal Sıçanların Genital Sistem Organlarında Ürotensin 2 Reseptörünün Karşılaştırılması

D Köse, Z Halıcı, E Toktay - Atatürk Üniversitesi Veteriner Bilimleri …, 2020 - dergipark.org.tr
Çalışmada sıçanlarda genital organlarda (over, uterus ve testis) puberte öncesi ve
sonrasında Ürotensin 2 Reseptör'ü (ÜTR 2) varlığını ve dağılımını karşılaştırmalı olarak …

[HTML][HTML] Disentangling the genomic architecture of psychosis in families with high prevalence through system genomic approaches

JP Fuster - 2021 - dialnet.unirioja.es
Los trastornos psicóticos como la esquizofrenia y el trastorno bipolar tienen una elevada
heredabilidad, sintomatología superpuesta, elevada heterogeneidad y susceptibilidad …