Substance use disorder (SUD) is common in psychiatric patients and has a negative impact
on health and well-being. However, SUD often goes untreated, and there is a need for …

Mammals have evolved with a range of innate drives, such as thirst and hunger, that
promote motivated behaviors to ensure survival. A drive for social engagement promotes …

The lateral habenula (LHb) has emerged as a pivotal brain region implicated in depression,
displaying hyperactivity in human and animal models of depression. While the role of LHb …

Stress is an important factor affecting human behavior, with recent works in the literature
distinguishing it as either productive or destructive. The present study investigated how the …

Stress is triggered by a threatening event that alters the regulation of emotion, behavior, and
cognition. The effects of stress on memory in animal models are well-documented. Firstly …

Objectives We examine the impact of sex and age on the effects of intense stress on action-
based (instrumental) and stimulus-based (Pavlovian) motivation for natural reward (food) …

Objectives Purposes were to identify subgroups of adult oncology patients (n= 1342) with
distinct joint profiles of worst pain and cognitive function (CF) and evaluate for differences in …

Although the acute stress response is a highly adaptive survival mechanism, much remains
unknown about how its activation impacts our decisions and actions. Based on its resource …

The medial prefrontal cortex (mPFC) resolves approach-avoidance conflicts and mediates
associative processes required for learning to avoid threats. Dopamine (DA) projections …

In many biparental mammals, such as California mice (Peromyscus californicus), fathers
display affiliative behavior toward unfamiliar infants whereas reproductively naïve adult …