Obstructive Sleep Apnea Syndrome (OSAS) is a respiratory sleep disorder characterised by
repeated episodes of partial or complete obstruction of the upper airway during the night …

Obstructive sleep apnea (OSA), characterized by intermittent hypoxia (IH), is linked with
increased reactive oxygen species/reactive nitrogen species (ROS/RNS) and oxidative …

Non-alcoholic fatty liver disease (NAFLD) represents the most common and emerging
chronic liver disease worldwide. It includes a wide spectrum of liver diseases ranging from …

Global epidemiological studies show that chronic non-communicable diseases such as
atherosclerosis and metabolic disorders represent the leading cause of premature mortality …

Obstructive sleep apnea (OSA) is a frequent disease mainly affecting obese people and
caused by repetitive collapse of the upper airways during sleep. The increased morbidity …

Nonalcoholic fatty liver disease (NAFLD) is the most common cause of chronic liver disease.
NAFLD includes a wide spectrum of liver conditions ranging from simple steatosis to …

Significance: The incidence of cardiovascular events (CVEs) increases with age,
representing the main cause of death in an elderly population. Aging is associated with …

Endothelial dysfunction is characterized by impaired endothelium-dependent vasodilatation
and is an independent predictor of adverse cardiovascular consequences. The ease with …

Recent studies underscore the proatherogenic role of hypoxia in macrophage lipid and
glucose metabolism, inflammation and polarization. These studies provide new insights into …

Intermittent hypoxia (IH) has been extensively studied during the last decade, primarily as a
surrogate model of sleep apnea. However, IH is a much more pervasive phenomenon in …