Regadenoson: a new myocardial stress agent

W Al Jaroudi, AE Iskandrian - Journal of the American College of …, 2009 - jacc.org
Vasodilator stress myocardial perfusion imaging (MPI) accounts for up to 50% of all stress
MPI studies performed in the US In 2008, the Food and Drug Administration approved …

A1 Adenosine Receptor Antagonists, Agonists, and Allosteric Enhancers

WF Kiesman, E Elzein, J Zablocki - Adenosine receptors in health and …, 2009 - Springer
Intense efforts of many pharmaceutical companies and academicians in the A 1 adenosine
receptor (AR) field have led to the discovery of clinical candidates that are antagonists …

Synthesis of pyrazoles from 1, 3-diols via hydrogen transfer catalysis

DC Schmitt, AP Taylor, AC Flick, RE Kyne Jr - Organic letters, 2015 - ACS Publications
Synthesis of Pyrazoles from 1,3-Diols via Hydrogen Transfer Catalysis | Organic Letters
ACS ACS Publications C&EN CAS Find my institution Log In Organic Letters ACS …

Electrosynthesis of N/S-heterocycles

J Wen, Y Yin, K Yan, B Li, MZ Zhang, J Yang - Green Chemistry, 2024 - pubs.rsc.org
The electrochemical generation of highly active and variable free radicals for the synthesis
of organic compounds has emerged as a favored approach due to its mild and …

[HTML][HTML] Regadenoson stress testing: a comprehensive review with a focused update

KO Elkholy, O Hegazy, A Okunade, S Aktas, T Ajibawo - Cureus, 2021 - ncbi.nlm.nih.gov
Regadenoson is a pharmacological stress agent that has been widely used since its
approval by the Food and Drug Administration (FDA) in 2008. For many years, dipyridamole …

A2A adenosine receptor and its modulators: overview on a druggable GPCR and on structure-activity relationship analysis and binding requirements of agonists and …

G Cristalli, C Lambertucci, G Marucci… - Current …, 2008 - ingentaconnect.com
Since the discovery of the biological effects of adenosine, the development of potent and
selective agonists and antagonists of adenosine receptors has been the subject of medicinal …

Current methods of pharmacologic stress testing and the potential advantages of new agents

EH Botvinick - Journal of nuclear medicine technology, 2009 - Soc Nuclear Med
This article presents the exciting advances made and ongoing in the area of pharmacologic
cardiac stress testing. In particular, new A2A-specific receptor agonists work like adenosine …

Recent Developments in Adenosine A2A Receptor Ligands

G Cristalli, CE Müller, R Volpini - Adenosine receptors in health and …, 2009 - Springer
The development of potent and selective agonists and antagonists of adenosine receptors
(ARs) has been a target of medicinal chemistry research for several decades, and recently …

The hydrazine moiety in the synthesis of modified nucleosides and nucleotides

A Guillou, S Peyrottes, J Vasseur, C Mathé… - …, 2024 - Wiley Online Library
Synthetic nucleoside mimics are re‐emerging as crucial contenders for antiviral and
anticancer medications. While, Ribavirin stands out for its unique antiviral properties …

General facile synthesis of 2, 5-diarylheteropentalenes

P Vachal, LM Toth - Tetrahedron letters, 2004 - Elsevier
Palladium-catalyzed cross-coupling reactions of various heteropentalene derivatives were
systematically studied. A general three-step synthesis of 2, 5-diarylheteropentalenes …