Recent advances in isobaric labeling and applications in quantitative proteomics

MK Sivanich, TJ Gu, DN Tabang, L Li - Proteomics, 2022 - Wiley Online Library
Mass spectrometry (MS) has emerged at the forefront of quantitative proteomic techniques.
Liquid chromatography‐mass spectrometry (LC‐MS) can be used to determine abundances …

Roles for the gut microbiota in regulating neuronal feeding circuits

BY Kristie, EY Hsiao - The Journal of clinical investigation, 2021 - Am Soc Clin Investig
The gut microbiota has the capacity to affect host appetite via intestinal satiety pathways, as
well as complex feeding behaviors. In this Review, we highlight recent evidence that the gut …

Recent advances in mass spectrometry analysis of neuropeptides

A Phetsanthad, NQ Vu, Q Yu… - Mass spectrometry …, 2023 - Wiley Online Library
Due to their involvement in numerous biochemical pathways, neuropeptides have been the
focus of many recent research studies. Unfortunately, classic analytical methods, such as …

Peptidome data-driven comprehensive individualized monitoring of membranous nephropathy with machine learning

Z Xu, R Chen, C Hao, Q Xie, C Deng, N Sun - Chinese Chemical Letters, 2024 - Elsevier
As the most common pathological type of nephrotic syndrome, membranous nephropathy
(MN) presents diversity in progression trends, facing severe complications. The precise …

Hyperglycemia effect of Pinctada martensii hydrolysate in diabetic db/db mice

J Li, Y Wei, S Huang, S Yan, B Zhao, X Wang… - Journal of …, 2024 - Elsevier
Abstract Ethnopharmacological relevance Pinctada martensii (Dunker) and other marine
shellfish flesh have been traditionally used in China as folk remedies regulate blood sugar …

Developing mass spectrometry for the quantitative analysis of neuropeptides

CS Sauer, A Phetsanthad, OL Riusech… - Expert review of …, 2021 - Taylor & Francis
Introduction Neuropeptides are signaling molecules originating in the neuroendocrine
system that can act as neurotransmitters and hormones in many biochemical processes …

Cocaine-Induced Remodeling of the Rat Brain Peptidome: Quantitative Mass Spectrometry Reveals Anatomically Specific Patterns of Cocaine-Regulated Peptide …

G Lu, F Ma, P Wei, M Ma, VNH Tran… - ACS chemical …, 2024 - ACS Publications
Addiction to psychostimulants, including cocaine, causes widespread morbidity and
mortality and is a major threat to global public health. Currently, no pharmacotherapies can …

11-Plex DiLeu Isobaric Labeling Enables Quantitative Assessment of Brain Region Protein Association Networks Impacted by the Gut Microbiome

S Han, Z Li, Y Shi, Y Cui, J Huang, DC Frost… - Analytical …, 2024 - ACS Publications
Gut microbiota can regulate host brain functions and influence various physiological and
pathological processes through the brain–gut axis. To systematically elucidate the …

Preventive effects of traditional Chinese medicine formula Huoxiangzhengqi against lipopolysaccharide-induced inflammatory response

M Gao, Z Zou, Y Qiu, G Sumayyah, X Jiang, J Su… - Phytomedicine, 2022 - Elsevier
Background Huoxiangzhengqi oral liquid (HX), a pharmaceutical product made from
traditional Chinese medicine formulas, has been commonly used in household medication …

Response boosting-based approach for absolute quantification of gelatin peptides using LC-MS/MS

S Han, Z Yan, X Huang, S Cai, M Zhao, Y Zheng, X Liu… - Food Chemistry, 2022 - Elsevier
Response-boosting of MS signal was observed in gelatin samples due to abundant Glycine
residues produced by collagen enzymolysis. In this work, a new strategy utilizing response …