Bioinspired claw-engaged and biolubricated swimming microrobots creating active retention in blood vessels

T Li, S Yu, B Sun, Y Li, X Wang, Y Pan, C Song… - Science …, 2023 - science.org
Swimming microrobots guided in the circulation system offer considerable promise in
precision medicine but currently suffer from problems such as limited adhesion to blood …

Gulf War illness: mechanisms underlying brain dysfunction and promising therapeutic strategies

B Dickey, LN Madhu, AK Shetty - Pharmacology & therapeutics, 2021 - Elsevier
Abstract Gulf War Illness (GWI), a chronic multisymptom health problem, afflicts~ 30% of
veterans served in the first GW. Impaired brain function is among the most significant …

Mechanistic insights into gut microbiome dysbiosis-mediated neuroimmune dysregulation and protein misfolding and clearance in the pathogenesis of chronic …

P Padhi, C Worth, G Zenitsky, H Jin… - Frontiers in …, 2022 - frontiersin.org
The human gut microbiota is a complex, dynamic, and highly diverse community of
microorganisms. Beginning as early as in utero fetal development and continuing through …

The complex molecular picture of gut and oral microbiota–brain-depression system: what we know and what we need to know

C Scassellati, M Marizzoni, N Cattane… - Frontiers in …, 2021 - frontiersin.org
Major depressive disorder (MDD) is a complex mental disorder where the neurochemical,
neuroendocrine, immune, and metabolic systems are impaired. The microbiota-gut-brain …

Opioid use, gut dysbiosis, inflammation, and the nervous system

R Jalodia, YF Abu, MR Oppenheimer, B Herlihy… - Journal of neuroimmune …, 2022 - Springer
Opioid use disorder (OUD) is defined as the chronic use or misuse of prescribed or illicitly
obtained opioids and is characterized by clinically significant impairment. The etiology of …

Enteric glial NLRP3 inflammasome contributes to gut mucosal barrier alterations in a mouse model of diet‐induced obesity

V D'Antongiovanni, M Fornai, R Colucci… - Acta …, 2024 - Wiley Online Library
Aim In the present study, we investigated the involvement of NLRP3 inflammasome in the
intestinal epithelial barrier (IEB) changes associated with obesity, and its role in the interplay …

Host Akkermansia muciniphila Abundance Correlates With Gulf War Illness Symptom Persistence via NLRP3-Mediated Neuroinflammation and Decreased Brain …

D Kimono, D Bose, RK Seth, A Mondal… - Neuroscience …, 2020 - journals.sagepub.com
Neurological disorders are commonly reported among veterans who returned from the Gulf
war. Veterans who suffer from Gulf War illness (GWI) complain of continued symptom …

Crisis in the gut: Navigating gastrointestinal challenges in Gulf War Illness with bioengineering

CA Collier, A Salikhova, S Sabir, S Foncerrada… - Military Medical …, 2024 - Springer
Abstract Gulf War Illness (GWI) is characterized by a wide range of symptoms that manifests
largely as gastrointestinal symptoms. Among these gastrointestinal symptoms, motility …

Obesity worsens gulf war illness symptom persistence pathology by linking altered gut microbiome species to long-term gastrointestinal, hepatic, and neuronal …

D Bose, P Saha, A Mondal, B Fanelli, RK Seth… - Nutrients, 2020 - mdpi.com
Persistence of Gulf War illness (GWI) pathology among deployed veterans is a clinical
challenge even after almost three decades. Recent studies show a higher prevalence of …

Pathophysiological basis and promise of experimental therapies for Gulf War Illness, a chronic neuropsychiatric syndrome in veterans

M Kodali, T Jankay, AK Shetty, DS Reddy - Psychopharmacology, 2023 - Springer
This article describes the pathophysiology and potential treatments for Gulf War Illness
(GWI), which is a chronic neuropsychiatric illness linked to a combination of chemical …