Over the last two decades, since the initial discovery of human papillomavirus (HPV) type 16
and 18 DNAs in cervical cancers by Dr. Harald zur Hausen (winner of the Nobel Prize in …

Cancer cell–derived extracellular vesicles (EVs) have unique protein profiles, making them
promising targets as disease biomarkers. High-grade serous ovarian carcinoma (HGSOC) is …

Cervical cancer is a public health issue in developing countries. Although the Pap smear
and colposcopy remain the major strategies for detection, most cases are diagnosed in the …

Chromosomal instability in early cancer stages is caused by stress on DNA replication. The
molecular basis for replication perturbation in this context is currently unknown. We studied …

Young age at first sexual intercourse (AFI) is an important risk factor for cervical cancer, but
no simple statistical model of its influence has been established. We investigated the …

The majority of human cervical cancers are associated with the high-risk human
papillomaviruses (HPV), which encode the potent E6 and E7 oncogenes. On prolonged …

Recurrent epidemics of influenza are due to the frequent emergence of antigenic variants.
With co-circulation of two influenza A subtypes and two antigenically distinct lineages of B …

Aurora B kinase (AURKB) inhibitors have been trialled in a range of different tumour types
but are not approved for any indication. Expression of the human papilloma virus (HPV) …

Ovarian surface epithelium (OSE) is considered to give rise to epithelial ovarian carcinomas
(EOCs). To elucidate early processes contributing to the development of EOCs from the …

Involvement of Ras in cancer initiation is known, but recent evidence indicates a role in
cancer progression, including metastasis and invasion; however, the mechanism is still …