Undiagnosed HIV infections may drive HIV transmission in the era of “treat all”: a deep-sampling molecular network study in Northeast China during 2016 to 2019

B Zhao, Y Qiu, W Song, M Kang, X Dong, X Li, L Wang… - Viruses, 2022 - mdpi.com
Universal antiretroviral therapy (ART,“treat all”) was recommended by the World Health
Organization in 2015; however, HIV-1 transmission is still ongoing. This study characterizes …

HIV phylogenetic clusters point to unmet hiv prevention, testing and treatment needs among men who have sex with men in kenya

F Cholette, L Lazarus, P Macharia, J Walimbwa… - BMC Infectious …, 2024 - Springer
Background The HIV epidemic in Kenya remains a significant public health concern,
particularly among gay, bisexual, and other men who have sex with men (GBMSM), who …

From components to communities: bringing network science to clustering for molecular epidemiology

M Liu, C Chato, AFY Poon - Virus Evolution, 2023 - academic.oup.com
Defining clusters of epidemiologically related infections is a common problem in the
surveillance of infectious disease. A popular method for generating clusters is pairwise …

Quantifying and predicting ongoing human immunodeficiency virus type 1 transmission dynamics in Switzerland using a distance-based clustering approach

M Labarile, T Loosli, M Zeeb, K Kusejko… - The Journal of …, 2023 - academic.oup.com
Background Despite effective prevention approaches, ongoing human immunodeficiency
virus 1 (HIV-1) transmission remains a public health concern indicating a need for identifying …

Increasing frequency and transmission of HIV-1 non-B subtypes among men who have sex with men in the Swiss HIV cohort study

JJ Duran Ramirez, T Ballouz, H Nguyen… - The Journal of …, 2022 - academic.oup.com
Abstract Background In Switzerland, HIV-1 transmission among men who have sex with men
(MSM) has been dominated by subtype B, whilst non-B subtypes are commonly attributed to …

Optimized phylogenetic clustering of HIV-1 sequence data for public health applications

C Chato, Y Feng, Y Ruan, H Xing… - PLOS Computational …, 2022 - journals.plos.org
Clusters of genetically similar infections suggest rapid transmission and may indicate
priorities for public health action or reveal underlying epidemiological processes. However …

Community Insights in Phylogenetic HIV Research: The CIPHR Project Protocol

F Cholette, L Lazarus, P Macharia… - Global Public …, 2023 - Taylor & Francis
Inferring HIV transmission networks from HIV sequences is gaining popularity in the field of
HIV molecular epidemiology. However, HIV sequences are often analyzed at distance from …

An approach to quantifying the interaction between behavioral and transmission clusters

L Salazar-Vizcaya, K Kusejko, HF Günthard, J Böni… - Viruses, 2022 - mdpi.com
We hypothesize that patterns of sexual behavior play a role in the conformation of
transmission networks, ie, the way you behave might influence whom you have sex with. If …

Community Insights in Phylogenetic HIV Research: The CIPHR Project Protocol

C François, L Lazarus, P Macharia, LH Thompson… - 2023 - erepository.uonbi.ac.ke
Inferring HIV transmission networks from HIV sequences is gaining popularity in the field of
HIV molecular epidemiology. However, HIV sequences are often analyzed at distance from …

Using longitudinally sampled viral nucleotide sequences to characterize the drivers of HIV‐1 transmission

ML Reichmuth, SE Chaudron, N Bachmann… - HIV …, 2021 - Wiley Online Library
Objectives Understanding the drivers of HIV‐1 transmission is of importance for curbing the
ongoing epidemic. Phylogenetic methods based on single viral sequences allow us to …